【正文】 .........................................29（五）RHLH 激動劑/拮抗劑 .......................................................................................................30三、腫瘤分子靶向和生物治療 ........................................................................................................31（一）生物反應(yīng)調(diào)節(jié)劑 ................................................................................................................31（二）單克隆抗體 ........................................................................................................................34（三）細(xì)胞分化誘導(dǎo)劑 ................................................................................................................37（四）細(xì)胞凋亡誘導(dǎo)劑 ................................................................................................................37（五）新生血管生成抑制劑 ........................................................................................................38（六）表皮生長因子受體抑制劑 ................................................................................................39（七）基因治療 ............................................................................................................................40 2（八）多靶點(diǎn)小分子抑制劑 ........................................................................................................40四、腫瘤治療輔助藥物 ....................................................................................................................42（一）造血生長因子 ....................................................................................................................42（二）止吐藥 ................................................................................................................................47（三）鎮(zhèn)痛藥 ................................................................................................................................49（四）抑制破骨細(xì)胞藥 ................................................................................................................52（五）神經(jīng)精神用藥 ....................................................................................................................53第四章 各類腫瘤的治療原則 ........................................................................................................57一、頭頸部惡性腫瘤 ........................................................................................................................57（一）鼻咽癌 ................................................................................................................................58（二）鼻腔和鼻旁竇惡性腫瘤 ....................................................................................................58（三）喉癌 ....................................................................................................................................59（四）甲狀腺癌 ............................................................................................................................62二、胸部腫瘤 ....................................................................................................................................63（一）非小細(xì)胞肺癌 ....................................................................................................................63（二）小細(xì)胞肺癌 ........................................................................................................................67（三）胸腺腫瘤 ............................................................................................................................69（四）惡性胸膜間皮瘤 ................................................................................................................70三、消化系統(tǒng)腫瘤 ............................................................................................................................71（一）食管癌 ................................................................................................................................71（二）賁門癌 ................................................................................................................................73（三）胃癌 ....................................................................................................................................73（四）結(jié)直腸癌 ............................................................................................................................75（五）膽管癌 、膽囊癌 ..............................................................................................................78（六）胰腺癌 ................................................................................................................................79（七）肝癌 ....................................................................................................................................81四、乳腺癌 ........................................................................................................................................82（一）復(fù)發(fā)轉(zhuǎn)移乳腺癌藥物治療 ................................................................................................83（二）可手術(shù)乳腺癌術(shù)后抗腫瘤藥物治療 ................................................................................85五、泌尿系統(tǒng)、男生殖系統(tǒng)腫瘤 ....................................................................................................87（一）腎上腺腫瘤 ........................................................................................................................87（二）腎臟腫瘤 ............................................................................................................................88（三）尿路上皮癌 ........................................................................................................................90（四）前列腺癌 ............................................................................................................................92（五）陰莖腫瘤 ............................................................................................................................96（六）睪丸腫瘤 ............................................................................................................................97六、婦科腫