hypothermia：低溫ppt課件-展示頁
2025-01-21 09:43本頁面
【正文】 g ? rigidity ? decr nerveconduction and areflexia Laboratory Manifestations ? CBC – hemoconcentration/thrombocytopenia ? Lytes – hyperkalemia/hypernatremia ? Bun/Cr – increased ? Glucose – intially increased then can be decreased ? Coags – increased ? ABG – hypercarbia/hypoxia/acidosis ? EKG – bradycardia/Osborne waves/atrial or ventricular arrythmias Osborne Waves Antipsychotics in Hypothermia ? Chlorpromazine (Thorazine) – attempts to use to induce hypothermia in 1950’s ? Multiple case reports of typical and atypical antipsychotics causing hypothermia ? Heh 1988 ?8 institutionalized patients with schizophrenia ?Measured oral temp off antipsychotics then on Haloperidol and then on Clozapine ?Oral temp dropped on both antipsychotics ?Greater drop with clozapine Antipsychotics in Hypothermia (cont) ? Scwaninger 1998 ?Describes 10 cases of hypothermia secondary to atypical antipsychotics reported to German Federal Institute for Drugs and Medical Devices ? Kramer 1989 ?Found 22% of older patients with hypothermia in one hospital were on antipsychotics (thioridazine most mon) Possible Mechanism ? Hypothalamus ?Dopamine re
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