疫4月17hypersensitivity-文庫吧資料
2024-08-24 14:34本頁面
【正文】 est (ii) Treatment 1. Desensitization 脫敏 1)Xenogenic antiserum 2)Allergen 2. Antihypersensitivity 抗過敏 167。 geic factors II Mechanisms Proteins 蛋白 Foods 食物 foreign serum 異種血清 nuts 堅果 vaccines 疫苗 seafood 海鮮 (fish,shrimp,shellfish,crab) (魚，蝦，貝，蟹 ) Plant Pollens 植物花粉 peas 豌豆 rye grass 黑麥 beans 菜豆 ragweed 豚草屬 eggs 蛋 timothy grass 梯牧草 milk 牛奶 birch trees 樺樹 mushroom 磨菇 (i) Allergens 過敏原(Anaphylactogens) Insect Products 昆蟲產(chǎn)物 bee venom 蜂毒 wasp venom 黃蜂毒液 ant venom 螞蟻毒液 cockroach calyx 蟑螂萼 dust mites 塵螨 Drugs 藥物 ? penicillin 青霉素 ? sulfonamides 磺胺 ? local anesthetics 局麻藥 ? salicylates 水楊酸鹽 Mold Spores 霉菌孢子 Animal Hair and Dander 動物毛及皮屑 (i) Allergens (Anaphylactogens) (ii) Ab: IgE Th1: IL2,IFNg,TNFb, IL12 Th2: IL4,5,6,10,13 IL4→ B→ IgE (IFNg inhibit IL4) (IL12 inhibit IgE) characteristics of IgE of IgE (1) IgE↑ (2) Ach↑ (3) Th2 ↑ (4) SIgA↓ (5) C1INH ↓ (C2a ↑ ) Allergic Individual過敏體質(zhì) (iii) IgEFceR+ cells mast cell, basophil 1) Distribution: mast cell: skin and submucosa。Chapter 20 Hypersensitivity 超敏反應(yīng) (Allergy, 變態(tài)反應(yīng) ) (Anaphylaxis, 過敏反應(yīng) ) Concept ? Allergen (Anaphylactogen) 過敏原secondly enter sensitized host. ? Immune responses (too strong!) that result in tissue injury or physiological dysfunction. History At first, of the glycerin extract of tentacles of Actiniaria(sea anemone)?？视吞崛∥? 22 days later, a second injection of the same amount the dog not ill the dog anaphylaxis Richet amp。 Portier, 1902 Hypersensitivity ? Type I Im
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