基因簇和基因重復ppt課件-文庫吧資料
2025-05-04 23:18本頁面
【正文】 es also may be generated as DNA copies of the mRNA sequences. An evolving set of genes may remain together in a cluster or may be dispersed to new locations by chromosomal rearrangement. The anization of existing clusters can sometimes be used to infer the series of events that has occurred. These events act with regard to sequence rather than function, and therefore include pseudogenes as well as active genes. Summary 。Part 1. Genes and genomes Chapter 4 Clusters and repeats 基因簇和重復序列 ?A gene family consists of a set of genes whose exons are related。 the members were derived by duplication and variation from some ancestral gene. ?A translocation is a rearrangement in which part of a chromosome is detached by breakage or aberrant rebination and then bees attached to some other chromosome. ?A gene cluster is a group of adjacent genes that are identical or related. Introduction ?Nonreciprocal rebination 不等交換 (unequal crossingover) results from an error in pairing and crossingover in which nonequivalent sites are involved in a rebination event. It produces one rebinant with a deletion of material and one with a duplicatio造成一個缺失一個重復 . ?Satellite DNA (Simplesequence DNA) 衛(wèi)星 DNAconsists of many tandem repeats (identical or related) of a short basic repeating unit. ?MinisatelliteDNAs小衛(wèi)星 DNAconsist of ~10 copies of a short repeating sequence. the length of the repeating unit is measured in 10s of base pairs. The number of repeats varies between individual genomes. Introduction Figure Unequal crossingover results from pairing between nonequivalent repeats in regions of DNA consisting of repeating units. Introduction Gene duplication is a major force in evolution Figure After
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