【正文】 Cover Letter 范例1投稿《歐洲心血管病雜志》1)Dear editorial board of European Journal of Cardiology,Please find enclosed the manuscript: “The angiotensinconverting enzyme is not a risk factor for myocardial infarction in French individuals”, by Sarah H., et al., to be submitted as a Short Communication to the European Journal of Neurology for consideration of coauthors have seen and agree with the contents of the manuscript and there is no financial interest to certify that the submission is original work and is not under review at any other this manuscript, we report the results of the first study on the genetic and functional roles of the ACE on the risk of suffering a myocardial infarction in the French , we genotyped the rs4341 polymorphism in 531 IS cases and 549 healthy controls, and then performed functional studies by measuring serum ACE protein level and activity in healthy controls, stroke patients at baseline and stroke patients 24h after stroke symptoms results from our study did not reveal any association of the ACE variant with myocardial infarction, although it affected ACE protein level, and ischemic stroke patients showed lower ACE level thancontrols in the acute phase but not in the chronic believe that our findings could be of interest to the readers of European Journal of Cardiology because they bring new and strong evidence that the ACE gene and protein are not a risk factor for myocardial hope that the editorial board will agree on the interest of this yours,Sarah behalf of the author: Sarah Hamilton at Cardiovascular Research Laboratory, Marie Curie Research Institute, 75000, Paris, France, xxx, phone number: +33582246xxx, fax number: + Letter 范例2《動脈粥樣硬化》的修改稿回復2)Dear DrEnzoMontanero,Thank you for considering the revised version of our manuscript ACE variants and risk of Cardiovascular Disease, by Sarah publication in are thankful to the referees and the Editor for pointing out some important modifications needed in the have thoughtfully taken into account these explanation of what we have changed in response to the reviewers’ concerns is given point by point in the following believe that the ments have been highly constructive and very useful to restructure the also believe that the new data included in the article really improved the quality of both our genetic and functional , we now show that the A allele of the rs10947 SNP of the ACE gene is a risk factor for all etiologies of cardiovascular disease(the association in the overall population resisted correction for multiple testing by Bonferroni).Moreover, we now show that mRNA levels of the ACE gene are higher in MI cases during the acute phase than in healthy controls or MI cases 3 months after the IS cases in the stable hope that all these changes fulfill the requirements to make the manuscript acceptable for publication in forward to hearing from you yours,Sarah Lucas Delphino on behalf of the author: Lucas Delphino at Alzheimer’s Disease Laboratory, Marie Curie Research Institute, 75000, Paris, France, xxx, phone number: +33582246xxx, fax number: +33582246xxx.。如果你的母語不是英語，可以讓朋友或?qū)I(yè)編輯服務公司幫忙較對和潤色。同時，你需要表明這項研究沒有發(fā)表過，而且也沒同時在別的期刊投稿。如果此項工作有與其他實驗室合作完成，你也可以在這里介紹相關合作團隊。再次，你可以介紹你和你的研究團隊：主要研究人員，實驗室的研究方向，以及與這篇文章的關系。同時，盡量讓編輯看到你的工作是和所投期刊非常相關的。一些臨床國際期刊還要求你介紹這項工作會對將來的實際治療應用有什么意義。其次，重點解釋為什么該研究是有創(chuàng)新性的而且會受大家感興趣。首先，向編輯簡要介紹一下論文的內(nèi)容以及參與此項研究工作的作者名單。太長的話會讓編輯感覺作者心虛，太短的話不足以充分表達文章所做工作