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20xx年醫(yī)學(xué)專題—他汀對糖尿病患者的作用(參考版)

2024-11-01 13:05本頁面
  

【正文】 ,。(用QRISK174??啥?74。舒降之174。ng)他汀以降低卒中和冠脈事件風(fēng)險(xiǎn)。297(11):11971206. doi:10.1001/jama.297.11.1197。ir243。)組:潘航、梁自文 創(chuàng)面組:歐秋果、蘭蘭、王靜,第四十七頁,共四十八頁。,第四十六頁,共四十八頁。 腎臟安全性良好。n)中獲益證據(jù)豐富且一致。 立普妥與其他他汀相比,能穩(wěn)定逆轉(zhuǎn)斑塊,在各類糖尿病人群(r233。i)服藥情況,第四十五頁,共四十八頁。nzhě)最后創(chuàng)面生長情況,(2016914),現(xiàn)在(xi224。)壞死肌腱,第四十四頁,共四十八頁。li225。 yā)吸引術(shù)后,第四十三頁,共四十八頁。 yā)吸引后,第四十二頁,共四十八頁。n shēn)抗感染、抗血小板聚集、降脂等治療,第四十一頁,共四十八頁。,術(shù)后第三天穿刺(chuānc236。oyǐng)及球囊擴(kuò)張術(shù) 脛前近段至中段彌漫性重度狹窄及遠(yuǎn)段重度狹窄處球囊擴(kuò)張術(shù)。r249。guǎn)病變處理,第三十九頁,共四十八頁。ngbi224。o)情況,第三十八頁,共四十八頁。,患者入院后用藥(y242。,我們(wǒ men)選擇的治療方案,保肢、血管介入治療 創(chuàng)面(chuāngmi224。n),類固醇性糖尿病 (1)糖尿病足(wagner 3級) (2)糖尿病周圍神經(jīng)病變 (3)糖尿病周圍血管(xu232。,2015.12.17 清創(chuàng)、換藥后,第三十五頁,共四十八頁。,第三十三頁,共四十八頁。 2015.12.15 ABI 左 0.7,右 0.67,雙下肢中度缺血。肝腎功能尚可 2015.12.15 C反應(yīng)蛋白:64.83 mg/L。n)、檢查,2015.12.15 血常規(guī):白細(xì)胞 7.18 109/L、中性(zhōngx236。jūn)培養(yǎng)+藥敏,第三十二頁,共四十八頁。,創(chuàng)面(chuāngmi224。,3,RESULTS,Southwest Hospital,Figure 2. Dapagliflozin attenuated atherosclerotic lesion formation in ApoE/ mice,第三十頁,共四十八頁。amp。 amp。 SD,per group. , p 0.05, , p 0.01 vs. DM + con。,2,RESEARCH METHOD,Southwest Hospital,All animals received human care and all study protocols were approved by the Institutional Animal Care and Use Committee of the Third Military Medical University before performance.,DM+dapa (n=12),DM+con (n=8),NDM+dapa (n=12),NDM+con (n=8),12weeks,treatment group,C57BL/6J (n=6),metabolic parameters,NLRP3 \IL1β \IL18,atherosclerotic lesion macrophages and smooth muscle cells,inflammatory cytokine,2. Measurements After 12week treatment, all mice were subject 8h fasting and then anesthetized and The bood was collected for metabolic data and inflammsome. The aortas were dissected Surgically under microscope and the fat was removed. The aortic root was OCTembedded and then made into
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