戴啟明醫(yī)師(參考版)
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【正文】 these three patients were extensive metabolizers. ? CONCLUSION: A 40 mg . dose of pantoprazole is sufficient to maintain pH in Korean patients, except for patients with extensive metabolizing CYP2C19 genotypes. 。 50:118593 9. Plainlanguage explanation ? 對於潰瘍有 再出血的高危險患者 ，氫離子阻斷劑的使用應(yīng)以高劑量為最有效 Pantoprazole ( 40mg/vial) intravenous 80 mg bolus and then 8mg/h ? 至於 40mg qd or bid 是否足夠可能要進(jìn)一步研究 Policy or practice change ? 1 amp qd iv可能不夠的，應(yīng)增加劑量 ? 健保 ? 謝謝大家 !! 6. Citations ? Lowdose intravenous pantoprazole for optimal inhibition of gastric acid in Korean patients. ? J Gastroenterol Hepatol. 2020 Sep。 (Produced by Bob Phillips, Chris Ball, Dave Sackett, Doug Badenoch, Sharon Straus, Brian Haynes, Martin Dawes since November 1998) ? Metaanalysis: protonpump inhibition in highrisk patients with acute peptic ulcer bleeding. ? Aliment Pharmacol Ther. 2020 Mar 15。 4 病例統(tǒng)計報告，以及質(zhì)量較不足的個案對照研究。 3 a 將同質(zhì)的個案對照研究 (case control studies)以系統(tǒng)性評論後的結(jié)果。 c 以多數(shù)結(jié)果為基礎(chǔ)的研究，及生態(tài)學(xué)的研究 (Outes research。 2 a 將同質(zhì)性的世代研究 (cohort studies)以系統(tǒng)性評論的結(jié)果。 b 具有嚴(yán)格的信賴區(qū)間的個別 RCT研究。 50:118593 Median pH profiles in eight healthy subjects after receiving an intravenous infusion of 80 mg of pantoprazole followed by 8 mg/hr as a constant infusion Julapalli V et al. Dig Dis Sci 2020。 74:3843 5Patchett SE et al. Gut 1989。 51(suppl 1): 5967 3Howden CW et al. Aliment Pharmacol Ther 1990。 prevention of ulcer re
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