【正文】
nalgesic potency and respiratory depressant properties morphine. 2)Used for acute pain。 3)neuroleptanalgesia 神經(jīng)(sh233。njīng)組織鎮(zhèn)痛,droperidol(氟哌啶醇)+ fentanyl,第五十五頁,共六十六頁。,Methadone 美沙酮,1) analgesic potency almost like morphine. 2) Used for acute pain. 3) often substituted for other opioids for treatment of physical dependence,第五十六頁,共六十六頁。,pentazocine 噴他佐辛(鎮(zhèn)痛(zh232。n t242。nɡ)新),1) the analgesic potency and inhibition of respiration morphine 2) Inhibits μ receptor and has less dependence . 3)Used for moderate pain.,非麻醉品,第五十七頁,共六十六頁。,dihydroetorphine 二氫埃托啡,1) 鎮(zhèn)痛作用為嗎啡的5001000倍, 2)作用僅2小時. 3)成癮性較嗎啡輕. 4)常用(ch225。nɡ y242。nɡ)于鎮(zhèn)痛或嗎啡類毒品成癮 者的戒毒。,第五十八頁,共六十六頁。,Section 3 Others,延胡索乙素、羅(顱)通定 (Corydolis ambigua、rotundine) 1) analgesic effect meperidine. 2)Used for chronic dull pain, 3) No effect on sharp pain. No addiction.,第五十九頁,共六十六頁。,Section 4 Opioid Antagonists,納洛酮、納曲酮 (naloxone、naltrexone),第六十頁,共六十六頁。,1)Block opioids receptors. 2)Used for opioid and other analgesics acute intoxication. 3)Use for diagnosis of addiction.,(納洛酮催癮實(shí)驗(yàn)(sh237。y224。n)),第六十一頁,共六十六頁。,小結(jié)(xiǎoji233。),Analgesic mechanism,Pharmacological Effects,Clinical Uses,第六十二頁,共六十六頁。,questions,Please describe the effects 、clinical uses and adverse reactions of morphine. 2. List the major uses of dolantin. 3. 心源性哮喘(xi224。ochuǎn)和支氣管哮喘(xi224。ochuǎn)能否使用嗎啡?簡述理由。,第六十三頁,共六十六頁。,good bye,第六十四頁,共六十六頁。,Thank you,第六十五頁,共六十六頁。,內(nèi)容(n232。ir243。ng)總結(jié),Chapter 19。Pain ? function disorders ? shock。Analgesic (鎮(zhèn)痛(zh232。n t242。nɡ))。嗎 啡 (夢神)。Analgesia 鎮(zhèn)痛(zh232。n t242。nɡ)。Sedation 鎮(zhèn)靜。pentazocine 噴他佐辛(鎮(zhèn)痛(zh232。n t242。nɡ)新)。dihydroetorphine 二氫埃托啡,第六十六頁,共六十六頁。,