淡豆豉中不同成分對(duì)高脂糖尿病大鼠肝臟和脂肪系數(shù)的影響-資料下載頁(yè)
2025-08-04 18:14本頁(yè)面
【正文】 sity, Beijing, 100023。 2．The Tirst Hospital of Xinji City in Hebei Province, Xinji, 052300。3. College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029）Abstract Objective: To investigate the influence of different ponents of of Semen sojae preparatum on liver and fat mass in high fat diet and diabetic rats. Methods: Diabetic model was induced by by high fat diet and low dose strep tozotocin ( STZ) injection. Rats were randomly divided into five groups: normal group, model group, aqueous extracts group , polysaccharides group and isoflavone from Semen sojae preparatum (ISSP) group. Rats were given intragastrically(ig) with aqueous extracts（8g medicinal material .）, polysaccharides（ .）and ISSP（2g .）for 28 days, while the normal and model group were treated with water. Blood sample was taken out from rats at the end of the experiments after 24 hours’ fasting for determination of SOD,MDA and serum lipid were tested, body weight, fat weight around kidneys and testis, fat index were detected. Results: Comparing with the normal group, the serum TC, TG, FAA, MDA and fat index in model group were obviously higher（P ，P ）,while LDL, and SOD were obviously lower（P ）. The above mentioned index was improved (P～) at the end of the experiments. Conclusions: extracts from Semen sojae preparatum could adjust serum lipid, decrease fat index, and the active ponents should be ISSP, polysaccharides took the second place.Key words: Semen sojae preparatum。 isoflavone。 polysaccharides。 lipid。 fat indexfat diet and diabetic7
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