sci論文寫作寶典(編輯修改稿)
2024-11-15 12:04 本頁(yè)面
【文章內(nèi)容簡(jiǎn)介】 rst study on the genetic and functional roles of the ACE on the risk of suffering a myocardial infarction in the French , we genotyped the rs4341 polymorphism in 531 IS cases and 549 healthy controls, and then performed functional studies by measuring serum ACE protein level and activity in healthy controls, stroke patients at baseline and stroke patients 24h after stroke symptoms results from our study did not reveal any association of the ACE variant with myocardial infarction, although it affected ACE protein level, and ischemic stroke patients showed lower ACE level thancontrols in the acute phase but not in the chronic believe that our findings could be of interest to the readers of European Journal of Cardiology because they bring new and strong evidence that the ACE gene and protein are not a risk factor for myocardial hope that the editorial board will agree on the interest of this yours,Sarah behalf of the author: Sarah Hamilton at Cardiovascular Research Laboratory, Marie Curie Research Institute, 75000, Paris, France, xxx@, phone number: +33582246xxx, fax number: + Letter 范例2《動(dòng)脈粥樣硬化》的修改稿回復(fù)2)Dear DrEnzoMontanero,Thank you for considering the revised version of our manuscript ACE variants and risk of Cardiovascular Disease, by Sarah publication in are thankful to the referees and the Editor for pointing out some important modifications needed in the have thoughtfully taken into account these explanation of what we have changed in response to the reviewers’ concerns is given point by point in the following believe that the ments have been highly constructive and very useful to restructure the also believe that the new data included in the article really improved the quality of both our genetic and functional , we now show that the A allele of the rs10947 SNP of the ACE gene is a risk factor for all etiologies of cardiovascular disease(the association in the overall population resisted correction for multiple testing by Bonferroni).Moreover, we now show that mRNA levels of the ACE gene are higher in MI cases during the acute phase than in healthy controls or MI cases 3 months after the IS cases in the stable hope that all these changes fulfill the requirements to make the manuscript acceptable for publication in forward to hearing from you yours,Sarah Lucas Delphino on behalf of the author: Lucas Delphino at Alzheimer’s Disease Laboratory, Marie Curie Research Institute, 75000, Paris, France, xxx@, p
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