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manifested in the following aspects : wisdom activation, wisdom design, intelligent processing, robotics, intelligent control, intelligent process planning, smart diagnostic, and other aspects. These innovative products are the key theoretical issues, but also by creating a door for a science skills in the important basic issues. The focus in these issues, we can form the basis of product innovation research system. 2. Modern mechanical engineering at the frontiers of science Crossintegration between the different science will produce new scientific gathering, economic development and social progress of science and technology created new demands and expectations, thus creating a frontier science. Frontier science is settled and unsettled issues between the scientific munity. Frontier science, with a clear domain, and dynamic character of the area. Works frontier science from the general basic science is an important characteristic of the actual works, it covers the key emerging science and technology issues. Ultrasonic electrical, ultrahighspeed machines, green design and manufacturing, and other fields, and has done a lot of research work, but innovation is the key question is not clear mechanical science. Large plex mechanical system design and performance optimization of product innovation design, smart structures and systems, intelligent robots and their dynamics, nano Mocaxue, manufacturing process 3D numerical simulations and physical simulation, precision and ultrafine processing technology key basis, about 10 mega large and sophisticated equipment design and manufacturing base, virtual manufacturing and virtual instruments, nanometer measurement and instrumentation, parallel connection axis machine tools, and although the field of microelectromechanical systems have done a lot of research, but there are still many key science and technology issues to be resolved. Information science, nano science, materials science, life science, management science and manufacturing science of the 21st century will be to change the mainstream science, and the resulting hightech industry will change the face of the world. Therefore, the above areas of crossdevelopment manufacturing systems and manufacturing informatics, nano manufacturing machinery and nano science, better machinery and better manufacturing science, management science and manufacturing systems will be critical to the 21st century mechanical engineering science is important frontier science. Manufacturing science and information science cross manufacturing informatics Mechanical and electrical products, chemical raw materials in the information. Many modern value added products primarily reflected in the information. Thus the manufacturing process for the acquisition and application of information is very important. Information science and technology is to create an important symbol of globalization and modernization. While the manufacturing technology began to explore product design and manufacturing processes, the nature of the information, on the other hand, to create technology to transform itself to adapt to the new information makes its manufacturing environment. Along with the manufacturing process and manufacturing systems to deepen understanding, researchers are trying to new concepts and approaches to their description and expression to achieve further control and optimization purposes.And manufacturingrelated information mainly product information, technical information and information management in this area following major research direction and content : (1) manufacturing information acquisition, processing, storage, transmission and application of knowledge to create information and decisionmaking transformation. (2) Nonsymbols expressing information, manufacturing information enables transmission, manufacturing information management, manufacturing information integrity in a state of nonproduction decisionmaking, management of virtual manufacturing, based on the network environment of the design and manufacturing, manufacturing process control and manufacturing systems science. These elements are manufactured in science and the scientific basis for the integration of product information, constitute the manufacture of the new branch of science to create informatics. Micro mechanical and manufacturing technology research Microelectronic mechanical systems (MEMS) refers to the collection of microsensors, microdevices and the implementation of signal processing and control circuits, interface circuits, munications and power with the integration of microelectromechanical system integrity. MEMS technology objectives through system miniaturization, to explore a new theory of integration, new functional ponents and systems. MEMS development will greatly facilitate the pocket of various products, miniaturization, a number of devices and systems to enhance the level of functional density, information density and Internet density, significantly saving, thin section. Not only can it reduce the cost of mechanical and electr