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jor drawback of this study is the limited number of cases, especially in the benign group, which may compromise the diagnostic power. Hence, a prospective clinical trial with more GGN cases is warranted to further evaluate and validate the diagnostic value of findings in this study. Additionally, this study could be strengthened if the analysis were conducted with a combination of vessel types and other GGN features, such as size and mass. Mass measurements can reflect lesion growth earlier with less variability than diameter measurements .,第三十八頁,共四十頁。,Tumour biology studies have revealed that vasculature remodelling or neoangiogenesis is one of the initiating events occurring in the early stage of tumour development. Therefore, analysis of GGNs and related blood supplying vessels could provide information on GGN differentiation. Small blood vessels and the relationships between vessels and lesions can be readily revealed and evaluated in CT images acquired with modern multidetector scanners, especially when imaging data are postprocessed using advanced computer techniques, including MPR and CPR. Many studies have demonstrated that relationships between SPNs and vessels, especially the vascular convergence sign (VCS), are valuable for estimation of the malignancy potential of SPNs,第三十二頁,共四十頁。,The vessel(s) traveling through GGN could be artery(ies) (category A), vein(s) (category B), or artery(ies) and vein(s)(category C). There were no significant differences and correlations between vascular categories and GGN groups(p =0.50 and 0.96, respectively) .,第二十五頁,共四十頁。2.5 mm, 9.3177。,Multiple supplying vessels, with different originating sources, converging toward a lesion, were probably indicative of an increased blood circulation within. To further clarify affiliations of supplying vessels, we traced vascular courses slicewise backward to major vessels in the hilum . The relationships between the GGNs and supplying blood vessels were analysed in axial images, MPR images CPR images.,第十四頁,共四十頁。 19 acinuspredominant adenocarcinomas。,Accurate differential diagnosis of GGNs will assist physicians to make treatment decisions and improve treatment outcomes and prognosis. Several investigators have suggested that analysis of relationships between SPNs and surrounding vessels can help predict the likelihood of malignancy in such nodules. The relationship between GGNs and blood vessels remains unknown. Whether this relationship can be utilised to facilitate the diagnosis of malignant GGNs is a worthy of investigation.,第六頁,共四十頁。,Key Points,Multidetector CT offers new information about ground glass nodules. Different types of groundglass nodules have different relationships with vessels. This may help identify which groundglass nodules are likely to be malignant.,第三頁,共四十頁。,According to pathological findings, GGNs were divided into three groups: Benign disease group (10 cases), including four nodules diagnosed with a combination of clinical symptoms and imaging presentations (nodules disappeared or gradually reduced in size on multiple followup CT imaging) and six nodules confirmed by pathological examination (1 case of sclerosing haemangioma and 5 cases of chronic inflammation). (2) Preinvasive disease group (24 cases), including 7 AAHs and