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? 首先發(fā)表的作者: Schmidt G ( Germany), Lancet,1999,353:1390 ? 檢測對象 :自主神經(jīng)的功能狀態(tài) ? 檢測方法 :應用動態(tài)心電圖檢測 TO/TS值, ( 1)震蕩初始( turbulence onset, TO ):檢出室早后是否有 A相 (先快 ) ( 2)震蕩斜率( turbulence slope, TS ):檢出室早后是否有 B相 (后慢 ) ? 正常值 : TO和 TS是兩個獨立的預測死亡危險性的指標, HRT分級: 0 TO 0、 TS ms/RR 正常 1 TO 0、 TS≤ ms/RR 或 TO ≧ 0、 TS 5 ms/RR 2 TO ≧ 0、 TS≤ ms/RR 明顯異常 ? 意義 :( 1) TO與 TS均異常是總死亡率敏感的預測指標,并有獨立的死亡預測的重要價值; ( 2) 現(xiàn)有資料顯示, HRT異常與死亡率增加相關(guān)。 2.負荷心電圖頻域分析法參考標準: ①靜息時,交替電壓( Valt) ≥, 交替率( K值) ≥3,持續(xù) ≥1min;②、運動后, Valt≥, K≥3,持續(xù) ≥1min;③、持續(xù)性電交替:無論何時①Valt≥、持續(xù) 1min或 1min以上, K≥3。計算機測得的正常人 QTd在 20~ 50ms之間。 1982年 Simson發(fā)展了此項技術(shù),應用雙向 Butter worth濾波,減少振鈴現(xiàn)象,可以實時地疊加、濾波增大,使很小的信號波能清晰地分辨出來。109:990–996. (五)壓力反射敏感性 ? 定義 :壓力反射敏感性是血壓變化導致反射性心率變化的敏感程度,是定量分析心臟自主神經(jīng)功能平衡狀況的指標之一 ? 首先發(fā)表的作者: Smyth HS Circ Res, 1969, 24: 109 ? 檢測對象 :BRS反映心率隨血壓變化而發(fā)生變化的速度 ,是交感神經(jīng)和副交感神經(jīng)張力變化的敏感指 標 ? 檢測方法 : 血管活性藥物法: 臨床上常規(guī)應用的可能是苯福林靜脈注射法。 35ms,③ RMSSD: 27177。 some advocate an upright cooldown period with a cutoff value of 12 beats per minute into recovery, whereas others support a sitdown recovery with a cutoff value of 22 beats per minute at 2 minutes into recovery.[2]When a supine recovery is mandated, as in stress echocardiography, a cutoff value of 18 beats per minute has been described.[3] K, et al. J Am Coll Cardiol. 1994。141:343–351 2020無創(chuàng) 心電指南 ? QRS prolongation could be simply a surrogate marker for more advanced myocardial disease, but it may also contribute directly to increased mortality, because dyssynchronous ventricular activation may cause depression of cardiac function[1] ? It has also been suggested that slow conduction and the associated increase in dispersion of ventricular recovery directly promote ventricular arrhythmias[2] ? The Coronary Artery Surgery Study registry found that pts with BBB had more extensive CAD, a lower mean LVEF, and higher 2year mortality than those with normal QRS duration. ? the presence of left bundlebranch block was an independent predictor of cardiovascular mortality due to SCD[3], a retrospective analysis of 669 pts with CHF of varying causes found that QRS duration ≥120 ms was independently associated with an increase in allcause mortality and SCD, especially in pts with LVEF ≤30%[4] [1]Park RC, et al. Circ Res. 1985。心電學預警心衰猝死的風險 中國醫(yī)學科學院 中國協(xié)和醫(yī)科大學 國家心血管病中心 阜外心血管病醫(yī)院 方丕華 中風 3 167,366 一、心臟猝死的概況 1 . Census Bureau, Statistical Abstract of the United States: 2020. 2 American Cancer Society, Inc., Surveillance Research, Cancer Facts and Figures 2020. 3 2020 Heart and Stroke Statistical Update, American Heart Association. 4 Zheng Z. Circulation. 2020。57:706 –717. [2]Akar FG, et al. Circ Res. 2020。24:1529–1535. 2. Shetler K, et al. J Am Coll Cardiol. 2020。 12ms ④ 三角指數(shù)( TRI): 37177。健康個體靜注苯福林 25~100μ g, 一般收縮壓升高> 20 mmHg, RR間期延長> 10 ms/mmHg。 ? 檢測方法 : 1.有創(chuàng)性直接記錄法: ( 1)心內(nèi)膜標測;( 2)心外膜標測 2.無創(chuàng)性體表記錄法: ( 1) 時域法; ( 2)頻域法 ? 正常值 : ① 信號平均后的 QRS波群時限( QRSD ) ≥120ms; ② QRS終末部 40181。國內(nèi)外公認 QTd正常值< 50 ms。 3.動態(tài)心電圖時域分析法參考標準: 為頻域分析方法的 4倍,即 Valt≥, K≥。但尚需要進一步的研究,以便明確 HRT在危險分層中是否具有臨床應用價值 . Heart Rate Turbulence ? in an ATRAMI substudy,[1] there was a relative risk of 4 in multivariate analysis. A posite auto