20xx年醫(yī)學(xué)專題—干細(xì)胞特性及最新研究進(jìn)展(精)-預(yù)覽頁
【正文】 刺激干細(xì)胞重組,將人類皮膚表皮和真皮細(xì)胞成功轉(zhuǎn)化成類似ES細(xì)胞的狀態(tài),從而制造出“人工誘導(dǎo)萬能干細(xì)胞”．這種培育出的干細(xì)胞與母體擁有相同的基因成分,因此不存在任何排斥問題．如果說21世紀(jì)是生命科學(xué)的世紀(jì),那么,干細(xì)胞研究將在生命科學(xué)研究中起著主導(dǎo)作用,相信,依靠人們的聰明才智,必定會在干細(xì)胞的研究和應(yīng)用方面取得可喜的成績,為人類的健康長壽帶來希望．參考文獻(xiàn):[1]Deutsch G,Jung J,Zheng M,et al．Abipotential precursor population for pancreas and liver within the embryonic endoderm[J]．Development,2011,128:871－881．[2]Gussoni E,Soneoka Y,Strickland,et al．Dystrophin expression in the mdx mouse restored by stem cell transplantation[J]．Nature,1999, 401:390－394．[3]Kocher AA,Schuster MD,Szabolcs MJ,et al．Neovascularization of ischemic myocardium by human bone marrow－derived ang ioblasts prevents cardiomyocyte apoptosis,reduces remodeling and improves cardiac function[J]．NatMed,2001,7:430－436．[4]Brazelton TR,Rossi FM,Keshet GI,et al．From marrow to brain: expression of neuronal phenotypes in adult mice[J]．Science,2000, 290:1775－1779．[5]Bjornson CR,Rietze RL,Reynolds BA,et al．Turning brain into blood:a hematopoietic fate adopted by adult neural stemcells in vivo [J]．Science,1999,283:534－537．[6]楊亞冬,張文元,陳勇．干細(xì)胞生物學(xué)特性及臨床應(yīng)用的研究進(jìn)展[J]．浙江省醫(yī)學(xué)科學(xué)院學(xué)報,2006,9(66:42－44．[7]White YA,Woods DC,Takai Y,Ishihara O,Seki H,Tilly JL．Oocyte formation by mitotically active germ cells purified from ovaries of reproductive－age women．Nat Med2012,18(3:413－21．[8]Doi D,Morizane A,Kikuchi T,Onoe H,Hayashi T,Kawasaki T,et al．Prolonged maturation culture favors a reduction in the tumorigenicity and the dopaminergic function of human ESC－derived neural cells in a primate model of Parkinson’s disease．Stem Cells2012。admixture。clinical application責(zé)任編輯:王志剛內(nèi)容總結(jié)
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