bridion174-sugammadex-全文預(yù)覽
【正文】 ? Indications: ? Used for adults undergoing surgery for the reversal of neuromuscular blockade (NMB) induced by rocuronium or vecuronium ? Not indicated to reverse blockade of nonsteroidal neuromuscular blocking agents (eg, succinylcholine) ? Not indicated for use in ICU setting Bridion174。 Sugammadex Clinical Application ? Pregnancy: ? No available human data ? In animal studies, fetal birthweight was reduced when 8x human dose was administered ? Lactation: ? Unknown excretion in human breast milk ? Present in animal milk Bridion174。 Sugammadex Drug Facts ? Drug Interactions: ? Hormonal contraceptives: must remend additional, nonhormonal method of contraception for next 7 days ? Toremifene: recovery can be delayed Bridion174。 Sugammadex Dosing Information ? Dosing: ? 24 mg/kg IV bolus based on actual body weight depending on blockade status ? Immediate Reversal: 16 mg/kg IV bolus based on actual body weight ? This dose has only been studied for rocuronium reversal Bridion174。18:99. ? Serious adverse effects were reported for 2 subjects in the sugammadex group and 3 in the
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鄂ICP備17016276號-1