【正文】
fantsSUN Ning*,SHEN Ying,SUN Qiang,LI xuran,ZHANG guiju,ZHANG weiping,CHEN zhi,F(xiàn)AN jianfeng,JIANG Yeping, FENG Dongchuan,ZHANG Ruifeng, ZHU Xiaoyu, XIAO Hongzhan. *Division of Urology, Department of Pediatric Surgery, Beijing Children’s Hospital Affiliated to Capital Medical University,Beijing 100045,ChinaCorresponding author:SHEN Ying (Email:ying_116sh)【Abstract】 Objective To summarize clinical characteristics, diagnosis and treatment of infants with urinary calculus and acute renal failure developed after being fed with melamine tainted formula milk. Methods Data of infant patients with urinary calculus and acute renal failure due to melamine tainted formula milk admitted to the Beijing Children’s Hospital affiliated to the Capital Medical University and the Xuzhou Children’s Hospital in 2008 were used to analyze the epidemiological characteristics, clinical manifestations, image features as well as effects of 4 types of therapies. Results All the 34 infants with urinary calculus were plicated with acute renal failure, their blood urea nitrogen (BUN) was ()mmol/L and creatinine (Cr) was ()μmol/L. The chemical analysis on the urinary calculus sampled from 14 of the infants showed that the calculus contained melamine and acidum uricum. The time needed for the four types of therapies for returning Cr to normal was () d for cystoscopy group, ()d for lithotomy group, ()d for dialysis group, and ()d for medical treatment group, which had no statistically significant difference(P=). Renal failure of all the 34 infants was rerelieved within 1 to 7 days, averaging () d. Conclusion Melamine tainted formula milk may cause urinary calculus and obstructive acute renal failure. It is suggested that firstly the patients with urinary calculus plicated with acute renal failure should be treated with dialysis or medication to correct electrolyte disturbances,in particular hyperkalemia, and then relieve the obstruction with available medical and surgical methods as soon as possible. It is observed that the short term prognosis is satisfactory.[Key words] Calculi; Urologic diseases; Kidney failure,acute; Melamine; Infants 照日 審改,2008104嬰幼兒泌尿系結(jié)石以往較為少見,近年來有增多趨勢,呈散發(fā)病例[1]。經(jīng)治療34例患兒急性腎