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Fields‖ 中有的字段只對部分數(shù)據(jù)庫起作用。從 2022年起,CLIB改由 Willey公司( John Wiley amp。 operator defaults to within six words。 Evidencebased Medicine 檢索時需要注意的一些問題 在檢索中尤其需要將主題詞檢索和關鍵詞檢索結合起來制定檢索策略; 對 標題 、 作者 字段的限定檢索可針對所有的數(shù)據(jù)庫;對 摘要 字段的限定檢索可針對 DARE和 Clinical Trails (CENTRAL) ; 對 publication type(出版物類型)字段的限定檢索僅針對 Clinical Trails (CENTRAL) 。 EMBASE( 1974年以來)MEDLINE( 1966年以來)的 1800多萬條生物醫(yī)學記錄。 ( 關聯(lián)詞 與 MEDLINE副主題詞 相似) EMTREE 每年更新 Evidencebased Medicine 分為 : 快速檢索 高級檢索 字段檢索 藥物檢索 疾病檢索 文章檢索 主頁為快速檢索 , 可使用自然語言檢索,可用單詞或詞組進行檢索,檢索詞組時需加單(雙)引號或連字符。 Evidencebased Medicine 三、如何檢索除書目數(shù)據(jù)庫以外的文獻 補充檢索與主題有關的數(shù)據(jù)庫 (supplementary subject databases) 檢索收錄各種指南的網(wǎng)站 (guidelines sites) 檢索會議摘要和學術會議錄網(wǎng)站 (meeting abstracts and conference proceedings) 檢索灰色文獻索引 (grey literature indexes) 檢索官方網(wǎng)站 (government/official websites) 檢索衛(wèi)生技術評估方面的網(wǎng)站 (other HTA websites) 檢索主要的在線書目數(shù)據(jù)庫 (major online book catalogues) 檢索已注冊和在研的臨床試驗數(shù)據(jù)庫 手工檢索相關雜志 Evidencebased Medicine 如何檢索除書目數(shù)據(jù)庫以外的研究文獻 還可參考 Cochrane Collaborationr的“ The Cochrane Handbook for Systematic Reviews of Interventions” (Version , updated September 2022)的相關內容 ( Sources to search)進行擴展檢索 (見以下幾張幻燈片的內容) Evidencebased Medicine 1. Journals and other nonbibliographicdatabase sources Handsearching Fulltext journals available electronically Tables of contents Conference abstracts or proceedings Other reviews, guidelines and reference lists as sources of studies Web Searching Evidencebased Medicine (1) Fulltext journals available electronically BioMed Central: PubMedCentral (PMC): Web sites listing journals offering free fulltext access include: Free Medical Journals: HighWire Press: Evidencebased Medicine (2) Tables of contents Many journals, even those that are available by subscription only, offer Table of Contents (TOC) services free of charge, normally through alerts or RSS feeds. In addition a number of anizations offer TOC services Evidencebased Medicine Examples of anizations offering Table of Contents (TOC) services British Library Direct (free): British Library Inside (to be replaced by British Library Direct Plus) (subscription): Current Contents (subscription): Scientific Electronic Library Online (SciELO) – Brazil (free): Evidencebased Medicine (3) specialist conference abstract sources Biological Abstracts/RRM (Reports, Reviews, Meetings): British Library Inside (to be replaced by British Library Direct Plus): British Library Direct Plus: /productsservices/bldplus ISI Proceedings: 從本校圖書館可查 Evidencebased Medicine (4) Other reviews, guidelines and reference lists as sources of studies Australian National Health and Medical Research Council: Clinical Practice Guidelines: Canadian Medical Association – Infobase: Clinical Practice Guidelines: National Guideline Clearinghouse (US): National Library of Guidelines (UK): New Zealand Guidelines Group: NICE Clinical Guidelines (UK): alguidelines/ Evidencebased Medicine 2. Unpublished and ongoing studies National and international trials registers Subjectspecific trials registers Pharmaceutical industry trials registers Trials results registers and other sources Evidencebased Medicine Examples of trials results registers International Federation of Pharmaceutical Manufacturers and Associations (IFPMA) Clinical Trials Portal: PhRMA Clinical Study Results Database: Research Findings Electronic Register (ReFeR) (no longer updated): BristolMyers Squibb Clinical Trial Results: Eli Lilly and Company Clinical Trial Registry: Roche Clinical Trials Results Database: Wyeth Clinical Trial Results: Evidencebased Medicine 有了機檢,為何還要手檢? 手工檢索雜志作為計算機檢索的補充至少有以下兩個原因: 1. 書目文獻數(shù)據(jù)庫并非對全部的臨床試驗文獻進行了收錄; 2. 雖然臨床試驗記錄被數(shù)據(jù)庫收錄,也可能由于在數(shù)據(jù)庫中使用的術語不易被識別出是臨床試驗而不能被檢索出來。 Evidencebased Medicine 為何要重視會議摘要? 從 《 系統(tǒng)評價者手冊 》 中可獲悉:“會議錄也是手工檢索的重要內容,因為會議錄常未被 MEDLINE等數(shù)據(jù)庫收錄。 《 文獻信息辭典 》 Evidencebased Medicine 為何要重視灰色文獻? 此外,灰色文獻一般來講比醫(yī)藥衛(wèi)生雜志報道有更多的陰性結果。如果假定某干預措施已發(fā)表的研究結果和未發(fā)表的研究結果相類似,沒有查找未發(fā)表的參考文獻不至于影響到系統(tǒng)評價的真實性( Validity),反之則將影響系統(tǒng)評價的真實性。 獲取未發(fā)表的文獻的途徑: 非正式的交流,向同行了解; 發(fā)出一個符合系統(tǒng)評價納入標準的相關研究信息的清單給有關人員; …… Evidencebased Medicine 為何需關注干預措施不良反應的信息? 有研究者指出:“評價任何醫(yī)學干預措施的應用,只知其有何益處顯然不夠,重要的是也應該知道它可能造成怎樣的危害。 如隊列研究、病例對照研究、無對照的臨床試驗、病例報告等。 Evidencebased Medicine 四、如何借鑒已有的檢索策略 借鑒已有的檢索策略最重要的一點是首先應弄清這些檢索策略是在何種檢索平臺上進行檢索的。不同的檢索平臺在檢索功能、檢索標識符等方面必然會有差異,任意套用就會出現(xiàn)問題。 Evidencebased Medicine 本講有關內容的說明 本講有關“ 更新系統(tǒng)評價檢索策略的制定 ”和 “ 如何借鑒已有的檢索策略 ”的文字部分請見本人發(fā)表在 《 中國循證醫(yī)學雜志 》 2022年第 7期上的 The Ccochrane Library ―new search‖圖標的特點及相關檢索策略分析 Evidencebased Medicine 小結(借用): Cochrane Handbook for Systematic Reviews of Interventions Sources to search Summary points (1) Cochrane review authors should seek advice from their Trials Search Coordinator on sources to search. CENTRAL is considered to be the best single source of reports of trials for inclusion in Cochrane reviews. The three bibliographic databases generally considered to be the most important sources to search for stu