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the center and a point on the curve。 it was finally proved impossible in the late 19th cent. (see geometric problems of antiquity). In modern mathematics the circle is the basis for such theories as inversive geometry and certain nonEuclidean geometries. The circle figures significantly in many cultures. In religion and art it frequently symbolizes heaven, eternity, or the universe. 。 a chord through the center is the diameter. A secant is a line of indefinite length intersecting the circle at two points, the segment of it within the circle being a chord. A tangent to a circle is a straight line touching the circle at only one point, the point of contact, or tangency, and is always perpendicular to the radius drawn to this point. A circle is inscribed in a polygon if each side of the polygon is tangent to the circle。 technically, the slope m of a straight line is the (trigonometric) tangent of the angle it makes with the xaxis. If the line is parallel to the xaxis, its slope is zero. Two or more lines with equal slopes are parallel to one another. In general, the slope of the line through the points (x1, y1) and (x2, y2) is given by m= (y2y1) / (x2x1). The conic sections are treated in analytic geometry as the curves corresponding to the general quadratic equation ax2+bxy+cy2+dx+ey+f=0, where a, b,?…?, f are constants and a, b, and c are not all zero. In solid analytic geometry the orientation of a straight line is given not by one slope but by its direction cosines, λ, μ, and ν, the cosines of the angles the line makes with the x, y, and zaxes, respectively。 the adoption of an approach to space in which all parts of the canvas played an equally vital role in the total work。s turbulent yet elegant abstract paintings, which were created by spattering paint on huge canvases placed on the floor, brought abstract expressionism before a hostile public. Willem de Kooning39。 and there are some of each type in the brain. These terms are used because nicotine mimics the action of acetylcholine at nicotinic receptors, whereas muscarine, an alkaloid from the mushroom Amanita muscaria, mimics the action of acetylcholine at the muscarinic receptors. Acetylcholine is the neurotransmitter produced by neurons referred to as cholinergic neurons. In the peripheral nervous system acetylcholine plays a role in skeletal muscle movement, as well as in the regulation of smooth muscle and cardiac muscle. In the central nervous system acetylcholine is believed to be involved in learning, memory, and mood. Acetylcholine is synthesized from choline and acetyl coenzyme A through the action of the enzyme choline acetyltransferase and bees packaged into membranebound vesicles . After the arrival of a nerve signal at the termination of an axon, the vesicles fuse with the cell membrane, causing the release of acetylcholine into the synaptic cleft . For the nerve signal to continue, acetylcholine must diffuse to another nearby neuron or muscle cell, where it will bind and activate a receptor protein. There are two main types of cholinergic receptors, nicotinic and muscarinic. Nicotinic receptors are located at synapses between two neurons and at synapses between neurons and skeletal