【正文】
1 核苷酸代謝 Nucleotide metabolism 2 核苷酸的生物功能 ?核酸合成的原料 synthesis materials for nucleic acid ?能量 Nucleotides Carry Chemical Energy in Cells ?代謝生理調(diào)節(jié) Some Nucleotides Are Intermediates in Cellular Communication ?組成輔酶 Nucleotides Are Components of Many Enzyme Cofactors ?活化中間代謝物 UDPG 3 Energy in Nucleotides 4 ? The phosphate ester and phosphoric acid anhydride bonds of ATP. Hydrolysis of an anhydride bond yields more energy than hydrolysis of the ester. A carbon anhydride and ester are shown for parison 磷酸酐 5 環(huán)化核苷酸 ? cAMP ? cGMP 6 Intermediates in Cellular Communication ? 細(xì)胞內(nèi)第二信使 ? ppGpp 是細(xì)菌內(nèi)在氨基酸缺乏時(shí)抑制 rRNA和tRNA合成的信使。 7 For protein modification ? 單聚 ADP核糖或多聚 ADP核糖對(duì)蛋白質(zhì)的修飾, ? 如白喉毒素常常催化受體蛋白質(zhì)加上單個(gè)ADP核糖, ? 白喉毒素活化的受體使 NAD上的腺苷二磷酸集團(tuán)轉(zhuǎn)移到 eEF2上,失活。 8 Nuclear protein digestion ? peptic acid proteins ? nuclear protein ? from food nucleic acids ? pancreas nuclease nucleotides pancreas,bowel n