【正文】
心房顫動(dòng)機(jī)制研究進(jìn)展 細(xì)胞核孔復(fù)合物與跨核運(yùn)輸障礙 華中科技大學(xué)生命科學(xué)與技術(shù)學(xué)院 華中科技大學(xué)人類(lèi)基因組研究中心 分子生物物理教育部重點(diǎn)實(shí)驗(yàn)室 王擎 故事的開(kāi)始: 常染色體隱性遺傳房顫家系 2 1 57 family members 32 males 25 females 5 living generations Age: 3 m93 y Autosomal recessive inheritance pattern 7 consanguineous marriages An Interesting Family Circulation, 2020 Oberti et al. Circulation, 2020。110:37533759 Proband V:11 Chronic AF QTc= s Delivered by caesarean section due to fetal tachycardia, HR of 250 bpm, atrial fibrillation and atrial flutter Echo at day 2: marked dilatation of both atria, EF 52% EP at 1 m detected AF, ablation of AV node Pacema