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roved (19962020) 1996 1997 1998 1999 2020 2020 2020 2020A c tu a l N u m b e rA p p r o v e d9 ? In 2020, out of 89 new drugs, no new antibacterial drugs were approved. ? Only about 5 new antibacterials in the drug pipeline, out of more than 400 agents in development* *According to annual reports of 15 major pharmaceutical panies Antimicrobial Availability 10 New Antibacterial Agents Approved Since 1998 Spellberg et al ANTIBACTERIAL rifapentine quinupristin/dalfopristin moxifloxacin gatifloxacin linezolid cefditoren pivoxil ertapenem gemifloxacin daptomycin YEAR 1998 1999 1999 1999 2020 2020 2020 2020 2020 NOVEL No No No No Yes No No No Yes 11 Phase III antibacterial development, December 2020 (