中國醫(yī)科大學附屬一院風濕免疫科張榕-文庫吧
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【正文】 membranous Class VI 腎小球硬化性 glomerulosclerosis 系統(tǒng)性紅斑狼瘡 Nervous system clinical manifestation: headache、 vomiting psychogenia epilepsy convulsion 、 conscious disturbance a pathologyvasculitis cerebrospinal fluidno special (intracranial pressure↑protein↑cell population↑ glucose↓) Identify with other central nervous system disease 系統(tǒng)性紅斑狼瘡 Hematology system leukopenia thrombocytopenia anemias: hemolytic anemias anemias of chronic disease lymphadenectasis splenectasis 系統(tǒng)性紅斑狼瘡 Respiratory system pleurisy Pleural effusion Pulmonary interstitial fibrosis Lupus pneumonia Pulmonary hypertension Respiratory failure 系統(tǒng)性紅斑狼瘡 lung 系統(tǒng)性紅斑狼瘡 Circulatory system heart pericarditis myocarditis endocarditis LibmanSack endocarditis cardiac arrhythmias cardiac failure vessel vasculitis 系統(tǒng)性紅斑狼瘡 Digestive system Clinical features anepithymia nausea and vomiting abdominal pain、 diarrhea peritoneal effusion acute abdomen pathology mesenterium vasculitis 系統(tǒng)性紅斑狼瘡 抗磷脂抗體綜合征 (antiphospholipid antibody syndrome) clinical manifestation: arterous and/or venous thrombosis spontaneous abortion thrombocytopenia laboratory examination: positive antiphospholipid antibody 系統(tǒng)性紅斑狼瘡 干 燥 綜 合 征 30%的 SLE患者可有繼發(fā)干燥綜合征 患者有臨床癥狀 唾液腺 ECT可有改變 干燥抗體可為陰性 系統(tǒng)性紅斑狼瘡 Etiology and pathogenesis pathology Clinical findings Laboratory findings Diagnosis Treatment prognosis 系統(tǒng)性紅斑狼瘡 一般檢查 自身抗體 補體等 狼瘡帶試驗 腎活檢病理 影像學檢查 血常規(guī) 尿常規(guī) 血沉 抗核抗體譜 抗磷脂抗體 抗組織 細胞抗體 C3 C4 CH50 Ig rG 診斷 治療 預后 MRI CT 實驗室和其他輔助檢查 SLE50% 代表 SLE 活動性 抗核抗體譜 抗核抗體 ANA 抗 dsDNA抗體 抗 ENA抗體 Jo1 Sm RNP SSB SSA 系統(tǒng)性紅斑狼瘡 Etiology and pathogenesis pathology Clinical findings Laboratory findings Diagnosis Treatment prognosis 系統(tǒng)性紅斑狼瘡 美國風濕病學會 (ACR)1997年 S
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