【正文】
唑巴坦 +++ ++++ ++++ + 克拉維酸 ++ +++ ++ ++++ 舒巴坦 +++ ++ +++ ++ 注:高 ++++;較高 +++;中等; ++;低 + 歐洲重癥監(jiān)護(hù)感染流行學(xué)會( EPIC) 14個歐洲國家 1417個 ICU10038患者統(tǒng)計 病原菌 發(fā)生率 ( %) 腸桿菌科 % 金黃色葡萄球菌 % 銅綠假單孢 % 凝固酶陰性葡萄球菌 % 真 菌 % Remendations (with ratings) for management of antimicrobial agent resistance 1. High level of carbapenemresistant P. eruginosa Reducec fluoroquinolone and ? or carbapenem use BIII 2. High level of fluoroquinolone resistant Reduce fluoroquinolone use and change primary drug to ciprofloxacin AI 3. High level of carbapenemresistant A. baumannii Reduce carbapenem use and assess for clonal problem AII L. R. Peterson, Clin Microbiol Infect 2022。 11 (Suppl. 5): 4–16 Remendations (with ratings) for management of antimicrobial agent resistance 4. High level of blactam resistance in P. aeruginosa Reduce extendedspectrum cephalosporin use and replace with piperacillin–tazobactam BIII 5. High level of ESBLproducing Enterobacteriaceae Reduce extendedspectrum cephalosporin use