膜分離技術(shù)-在線瀏覽
2024-09-11 17:52本頁面
【正文】 性膜 膜質(zhì)分兩層：功能層、支持層 流速高，不易堵塞 BioPharm An electronmicrograph image of a crosssection of a Ultrafiltration doublewalled hollow fiber membrane. BioPharm Types of Filtration To reduce fouling two process modes exist: Feed Permeate Permeate Feed Retentate 1. Deadend 2. Crossflow Cake layer BioPharm Type 1: Dead End Flow ? Flow perpendicular to membrane surface ? Causes build up of filter cake on membrane ? F = feed。 P = permeate (ponents that pass through membrane) Deadend Flow diagram from: BioPharm Dead End Mode BioPharm Type 2: Cross Filtration ? Flow parallel to membrane surface ? Does not cause buildup, therefore does not suffer from reduced flow overtime ? F = feed。 P = permeate。m) ? High removal efficiency of bacteria and viruses ? OutsideIn flow configuration that allows for less plugging and higher solids loading, higher flow area and easier cleaning ? Can be periodically back washed and air scoured to improve performance and extend operating life by removing the fouling layer ? Simple, vertical, modular design allows low cost, pact systems [3] BioPharm Advantages ? 使用壽命長：超濾采用特別性能的 PVDF材料并經(jīng)過親水改性，具有極佳的抗氧化性和抗疲勞強(qiáng)度，抗污染，耐清晰，大大延長了膜絲的使用壽命。 ? 適用范圍廣：超濾的外壓式結(jié)構(gòu)和專利的布水方式，容許更寬的進(jìn)水懸浮物含量，更適合于水質(zhì)較差的應(yīng)用條件，并同時(shí)保證很高的水回收率。 BioPharm Hollow fiber: BioPharm Spiral wound BioPharm BioPharm BioPharm Ceramic Membrane Elements BioPharm BioPharm BioPharm Spiral UF system BioPharm 離心管式超濾器 BioPharm 實(shí)驗(yàn)室 BioPharm Microfiltration vs. Ultrafiltration ?Microfiltration: ?Proteins act as the permeate Images from: technology/ftech ?Ultrafiltration ?Proteins act as the retentate BioPharm Microfiltration vs. Ultrafiltration ?Microfiltration: ?Separates larger particles ?For example ?Colloids ?Fat globules ?Cells ?Located upstream to reduce load and fouling capacity on ultrafiltration membrane downstream ?Ultrafiltration ?Separates smaller particles ?For example ?Macromolecules However, processes are basically identical BioPharm Applications: ?food and dairy industry (the concentration of milk and cheese making, the recovery of whey proteins, the recovery of potato starch and proteins, the concentration of egg products, the clarification of fruit juices and alcoholic beverages) ?pharmaceutical industry (enzymes, antibiotics, pyrogens熱源 ) ?textile industry ?chemical industry ?metallurgy (oilwater emulsions, electropaint recovery) ?paper industry ?leather industry ?sub layers in posite mebranes for nanofiltration, reverse osmosis, gas separation or prevaporation BioPharm 超濾技術(shù)在人血白蛋白濃縮中的應(yīng)用 ? 超濾器 日本富士公司生產(chǎn)的 Filtron系統(tǒng)，超濾膜切割分子量為 8 000(道爾頓 )． ? 操作方法 ? 將 Chon氏法分離的沉淀 v，用 蒸餾水溶解 至蛋白濃度大約為質(zhì)量分?jǐn)?shù) 5％， ? 用 EK澄清板先將蛋白溶液 過濾處理 ，去除不溶解物質(zhì)，防止超濾過程中將超濾器堵塞 ? 將澄清后的蛋白溶液進(jìn)行 超濾 ，氣源壓強(qiáng)為 ～ MPa，工作壓強(qiáng)為～ MPa，超濾液用雙縮脲法、三氯醋酸法或磺基水楊酸法檢驗(yàn)不可有蛋白陽性反應(yīng)，超濾液棄去 ? 預(yù)濃縮 —— 循環(huán)超濾至蛋白濃度約為 7％時(shí)停止?jié)饪s ? 將預(yù)濃縮后的蛋白液繼續(xù)超濾，同時(shí)向蛋白液內(nèi)加入與超濾液等容的蒸餾水，進(jìn)行 連續(xù)洗滌脫醇超濾 ．蒸餾水洗脫總量為原蛋白溶液體積的 6倍，這時(shí)殘留的乙醇已被洗滌至低于
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