[水產(chǎn)漁業(yè)]20xx免疫刺激劑-文庫吧資料
2024-10-20 14:48本頁面
【正文】 五條鰤（ Seriola quinqueradiata）對(duì)鏈球菌病和日本對(duì)蝦（ Penaeus japonicus）對(duì)弧菌病與病毒性血癥的抵抗力。 ? 作為疫苗的佐劑增強(qiáng)抗原細(xì)胞的信號(hào)分子被有效呈遞，促進(jìn)淋巴細(xì)胞產(chǎn)生抗體。 B lymphocytes ? Activate phagocytes ? Activate plete system ? 通過血小板溶解釋放多種藥理活性物質(zhì) ? 誘發(fā)抗體的產(chǎn)生和補(bǔ)體的生成 Effects of Peptidoglycan in aquaculture ? 混飼（ 660mg/kg體重或 ） ? 降低條件致病菌感染引起的死亡率，預(yù)防病毒感染，防御寄生蟲侵襲。 Beta Glucan in aquaculture ? 與體液因子及免疫細(xì)胞的特異受體結(jié)合 ? 1530mg/kg體重或 ? In fish – 促進(jìn) MФ向病灶轉(zhuǎn)移， ROS?， 抗病毒、抗應(yīng)激 ? – 顯著提高疫苗效價(jià) ? In shellfish – PO（酚氧化酶原系統(tǒng)） activity – 通過多種途徑參與機(jī)體的防御反應(yīng) 附：蝦蟹貝類的免疫系統(tǒng) ? Hemocytes ? prophenoloxidase →phenoloxidase, PO →氧化酪氨酸、 二羥基苯丙氨酸等 →生成苯醌中間產(chǎn)物 →最終生成黑色素 Oyster hemocyte Peptidoglycan amp。HCl Levamisole ? Anthelminthic drug ? In mammals –↑metabolic and phagocytic activities of neutrophils –↑ number of phagocytes and leucocytes –↑ level of lsozyme in serum In Coho salmon and Carp ? Injection of levamisole + modified Freund’s plete adjuvant increased Coho salmon’s resistance to A. salmonicida. ? Injection of levamisole increased the phagocytic activity and myeloperoxidase activity of neutrophils, leucocyte numbers and serum lysozyme levels in carp. In Rainbow trout Injection of levamisole （ ） ? ↑Resistance to Vibrio anguillarum ? ↑Phagocytic activity and chemiluminescance responses of leucocytes ? ↑NK cell a
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