【正文】 bin (oxyhemoglobin, methemoglobin, carboxyhemoglobin) and other projects, more convenient clinical diagnosis and treatment. A variety of automatic biochemical analyzer with ion selective electrode technology rich Determination of content, immunochemical means that once belonged in the history of Bacteriology and Immunology, content, until recent years, both near for analysis turbidimetric determination of the antigenantibody plexes, Therefore a lot of automatic biochemical analyzer set turbidimetry and nephelometry. Later, various marker techniques such as ELISA technology, lightemitting technology (fluorescence, chemical, electrochemical techniques) are successively applied to the test zone network in clinical chemistry, clinical chemistry and immunology bined RIA technology, developed a lot of automatic biochemical analyzer. Testing of these instruments has been very extensive, radiation to the fields of pathogens, endocrine, tumor markers, drug monitoring, determination of enzymes and isozymes, which not only cross with traditional biochemical automatic analyzer in the measurement item, but technically penetration, both from the technical integration of the development of versatile automatic biochemical analyzer. A key part of a variety of automatic biochemical analyzer or test and analysis system, limited to the photometric analysis, converted into electricity through changes in luminosity (including color and turbidity) to analyze changes in the sample, in order to produce this luminosity changes, and a reagent react, and this reaction specificity and sensitivity of the samples required by the features of the pretreatment reagent test, in order to obtain the desired results. In recent years, the emergence of a variety of biological sensors, can take to change this determination, a variety of biosensors biochemical reactions into electrical signals, can take advantage of the automatic biochemical analyzer to monitor and process electrical signals change, fully automatic analysis create the latest biosensorautomatic biochemical analyzer.2, automatic biochemical analyzer and related technologies For the clinical laboratory automated process to keep up with the level of developed countries in the international development of automatic biochemical analyzer is the preferred subject of domestic Laboratory Medicine, this domestic R amp。 D time has urgent automatic biochemical analyzer, over the past decade, China has independently developed a variety of models sold nearly the clinical diagnosis of the test zone network semiautomatic biochemical analyzer analytical instruments. On this basis, the relevant R amp。 D units of domestic strength and developing technical solutions for the development of automatic biochemical analyzer, the entire program is divided into three stages: the first stage for the development of the analytical sample speed reached 200 Test / h automatic biochemical analyzer development cycle for about 2 years, to reach the lower level。 reached the second phase for the development of 300 Test / h or more largecapacity multichannel automatic biochemical analyzer。 The third stage is the development of biosensing type automatic analysis instrument , there must be a new breakthrough in the field of analysis.The key technology is the development of the first phase of the automatic biochemical analyzer: ① mechanical and electrical integration of threedimensional precision mechanical systems, sample transfer, reagent feeding and positioning, the cleaning of the sampling needle and sample reagent mixing and conveying, by the pletion of the threedimensional mechanical systems, similar to a mechatronic robot。 ② highprecision sample collection system, reagents the quantitative and sample quantitative, by the pletion of this system, it requires highprecision, due to the sample collection is generally only 3 5 ul of the size of its acquisition amount, directly affect the measurement results。 ③ control techniques to achieve 176。 C。 ④ monochromatic spectrum automatic precision optical system, it is a sampling system。 ⑤ Analysis software.The key technology of the development of the second phase of the automatic biochemical analyzer is a multichannel measurement technology, and development of a single light source, multichannel beam sensing technology.The third phase of the development of biosensing automatic biochemical analyzer key technologies for a variety of sensors, such as enzymes sensor, microbial sensor, immune sensor, organization sensor. Its very difficult to put into technology, material resources.For the first phase of development of the project, technically there is no special difficulty, the implementation of this development project, to build a testing laboratory in order to make automatic biochemical analyzer key ponent parameters, in line with the requirements of the whole, the second phase of the development of largescale automatic biochemical analyzer, the technical challenges need to organize multichannel, multidisciplinary technical personnel to deal with this critical technology. For the third stage of the biosensorbased automatic raw by the analyzer, then create a biosensor laboratory, advance R amp。 D in the middle of the first phase of the by biochemical electronic technical personnel.Because it is a selfdeveloped core technology, the threestage step is necessary due to limited manpower and material resources, the third phase of the development will be on the basis of the development of the first phase of the project, only plete the first phase of the R amp。 D projects and clinically confirmed in order to ensure the development and implementation of the second and third stages of the research and development of such a plan a long time, if there is financial support, would reverse time on the passive and the demand for talent, the development of various biosensor is a multidisciplinary cuttingedge science, requires a lot of material and human reso