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, HCO3 5 mmol/L, Na 140 mmol/L, K 4.0 mmol/L, Cl 115 mmol/L Calculation AG = 140 – 115 – 5 = 20 ?PCO2 = 11 mmHg Interpretation Mixed hyperchloremic and high AG metabolic acidosis,第二十六頁,共四十六頁。,Is There A Simple Way ?,第二十七頁,共四十六頁。,Mixed AcidBase Disorders,ABG pH 7.32, PCO2 28 mmHg, HCO3 14 mmol/L, BUN 100 mmol/L Interpretation Acidemic with low PCO2 and low bicarbonate concentration Low bicarbonate as a primary disorder – metabolic acidosis (secondary to renal failure) PaCO2 30 in the presence of low HCO3 – primary respiratory alkalosis,PaCO2 30 in the presence of low HCO3 – primary respiratory alkalosis,第二十八頁,共四十六頁。,Mixed AcidBase Disorders ?,ABG pH 7.12, PCO2 88 mmHg, HCO3 28 mmol/L Interpretation Acidemic with high PCO2 and high bicarbonate concentration High PCO2 as a primary disorder – respiratory acidosis (secondary to cor pulmonale) HCO3 30 in the presence of acutely elevated PCO2 – primary metabolic alkalosis HCO3 45 in the presence of chronically elevated PCO2 – primary metabolic alkalosis,HCO3 30 in the presence of acutely elevated PCO2 or HCO3 45 in the presence of chronically elevated PCO2 – primary metabolic alkalosis,第二十九頁,共四十六頁。,Mixed AcidBase Disorders ?,ABG pH 7.50, PCO2 38 mmHg, HCO3 31 mmol/L, K 3.5 mmol/L Interpretation Alkalemic with low PCO2 and high bicarbonate concentration High HCO3 as a primary disorder – metabolic alkalosis PCO2 55 in the presence of elevated HCO3 – primary respiratory alkalosis,PCO2 55 in the presence of elevated HCO3 – primary respiratory acidosis,第三十頁,共四十六頁。,Mixed AcidBase Disorders ?,ABG pH 7.48, PCO2 29 mmHg, HCO3 23 mmol/L Interpretation Alkalemic with low PCO2 and normal bicarbonate concentration Low PCO2 as a primary disorder – respiratory alkalosis (secondary to asthma) HCO3 20 in the presence of acutely decreased PCO2 – primary metabolic acidosis HCO3 15 in the presence of chronically decreased PCO2 – primary metabolic acidosis,HCO3 20 in the presence of acutely decreased PCO2 or HCO3 15 in the presence of chronically decreased PCO2 – primary metabolic acidosis,第三十一頁,共四十