cervicalcancerhpv(編輯修改稿)
2024-11-23 04:17 本頁面
【文章內(nèi)容簡介】 een annually with regular Paps or every 2 years with liquidbased tests ? After three normal tests, can go to every three years ? Stop at 6570 years with history of negative tests ? Still need annual checkups Cervical Cytology Screening. ACOG Practice Bulletin No. 45. 2020。 102:41727. 17 NEW! The HPV Vaccine Gardasil 174。 (Merck) ? Protects against types 16, 18, 6, 11 ? FDA approved for use in females 926 years of age ? Prevents HPV infection。 doesn’t treat existing infection ? Viruslike particles (VLP) ? Highly effective ? Safe, few serious adverse side effects ? Requires 3 injections ? Expensive ($360 + administrative fees) Smith, RA et al. Cancer. 2020。53(1): 2743. 18 HPV Vaccine ACOG Remendations VACCINATE all females 926 years old, regardless of sexual activity ? Less potential benefit with increasing age amp。 number of sexual partners Special populations – vaccine less effective ? Previous abnormal Pap tests or genital warts ? Immunopromised Continue screening with Pap tests! Human Papillomavirus Vaccination. ACOG Committee Opinion No. 344. 2020。 108: 699705. 19 NOT CURRENTLY RECOMMENDED (Awaiting more evidence) Continue screening with Pap tests! ? Women over age 26 ? Pregnant women – If vaccine started before pregnancy, give remaining dose(s) postpartum ? Breastfeeding women ? Men HPV Vaccine ACOG Remendations Human Papillomavirus Vaccination. ACOG Committee Opinion No. 344. 2020。 108: 699705. 20 HPV Vaccine Important Considerations Continue screening with Pap tests! ? Vaccine is most effective before first sexual intercourse – less effective in sexually active women ? HPV testing before vaccine not remended ? Vaccine is not a treatment for current HPV infection, genital warts, or precancer Human Papillomavirus Vaccination. ACOG Committee Opinion No. 344. 2020。 108: 699705. 21 HPV Vaccine FAQ ? Vaccine will not cause HPV – Viruslike particle vaccine (not live virus) ? HPV vaccines appear to be very safe – Few major adverse events, but limited data ? Most side effects are minor – Injection site reaction ? Potentially effective in preventing cervical cancer (and other HPVrelated cancers) – BUT not all cancercausing HPV types are covered by the vaccine Continue screening with Pap tests! Human Papillomavirus Vaccination. ACOG Committee Opinion No. 344. 2020。 108: 699705. 22 References Advisory Commi
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