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ed alone. ? There is no evidence that stroke patients with a normal heart rhythm benefit from anticoagulants. Abstracts: Cochrane Review ? In most ischaemic strokes, the blockage is caused by a blood clot. Anticoagulant drugs, such as warfarin, may prevent such clots forming and hence could prevent stroke. However, anticoagulant drugs may also cause bleeding in the brain and this plication could offset any benefits. This review identified a number of trials, in patients who had had a stroke, of anticoagulants to prevent further strokes. There was good evidence that anticoagulants could cause serious bleeding, and there was no evidence that anticoagulants were of benefit. However, other trials show that patients with an irregular heartbeat (atrial fibrillation) and a recent stroke due to a blocked artery do benefit from anticoagulants. New trials are underway to see whether stroke patients with a normal heart rhythm can get greater benefit from anticoagulants than from standard clotpreventing treatments such as aspirin and other antiplatelet drugs. P Sandercock, O Mielke, M Liu, C Counsell。 Antico