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ical role in all organism. It determines the protein folding, stabilizes the double helix structure of DNA. If we substitute deuterium for hydrogen, the biological system may be destroyed. Many physical and mathematical approaches can be applied to biology such as the quantum mechanics, nonequilibrium thermodynamics, information theory. But a basic difficult by using the nonequilibrium thermodynamics in biology is the spatial heterogeneity in biological systems and the feedback existing in all kinds of reactions and processes. Condensed Matter Physics also concerns closely with Biophysics. The theory of phase transitions and critical phenomena can be used to explain problems such as how the temperature of the phase transition of lipids from the solid state to the liquid crystalline depends on the fatty acid position. On the other hand, researches in biophysics also push forwar