【正文】 ang X,Carpenter D,Bokui N, et al .Overexpression of Nell1,a craniosynostosisassociated gene, induces apoptosis in osteoblasts during craniofacial development[J]. Bone Miner Res,2021,18(12): 21262134 [13] Lieberm an JR,Daluiski A,Einhom role of growth factor in the repair of and clinical applications[J]. Bone Joint Surg,2021,84A(6):10321044 [14] . ElGheriani, . Maher, . ElGheriani, et al. Marazita Segregation Analysis of Mandibular Prognathism in Libya [J]. Dent Research 2021, 82(7):523527 [15] Ricardo Machado Cruz,Henrique Krieger, Ricardo Ferreira, et al. Major Gene and Multifactorial Inheritanceof Mandibular Prognathism [J] .American Medical Geics ,2021,146A(1):7177 [16] Stockton DW,Das P,Goldenberg M, et of Pax9 is associated with oligodontia[J].Nat ,24(1):1819 [17] Zhou J, Lu Y, Gao XH, et al. The growth hormone receptor gene is associated with mandibular height in a Chinese population[J]. Dent Res, 2021,84(11):10521057 [18] Zhang X, Kuroda S, Carpenter D, et al .Craniosynostosis in transgenic mice overexpressing Nell1 [J]. Clin Invest,2021,110(6):861870 [19] Lander new genomics:global views of biology[J].Science,1996,274(5287):536539 [20] David G, identification mapping and genotyping of single nuclotide polymorphisms in the human genome[J].Science,1998,280(5366):10771082 [21] Lai of SNP technologies in medicine:lessons leamed and future challenges[J].Genome Res,2021,11(6