【正文】
,24,第二十四頁,共二十五頁。,病例(b236。三組術(shù)后鎮(zhèn)痛持續(xù)劑量2 mL/h。ngm224。nzhě)隨機(jī)分三組,每組20人; control組靜脈和關(guān)節(jié)腔內(nèi)給予N.S;intraarticular組靜脈給予N.S,關(guān)節(jié)腔內(nèi)給予DEX; i.v. 組靜脈給予DEX,關(guān)節(jié)腔內(nèi)給予N.S ;〔DEX 1 ug/ kg〕 結(jié)論:關(guān)節(jié)內(nèi)應(yīng)用優(yōu)于靜脈應(yīng)用優(yōu)于對(duì)照,AlMetwalli, R. R., H. A. Mowafi, et al. (2022). “Effect of intraarticular dexmedetomidine on postoperative analgesia after arthroscopic knee surgery.“ Br J Anaesth 101(3): 395399.,8,第八頁,共二十五頁。,3,第三頁,共二十五頁。,鎮(zhèn)痛作用(zu242。,10,第十頁,共二十五頁。i),Iwakiri, H., Y. Oda, et al. (2012). “The efficacy of continuous infusion of low dose dexmedetomidine for postoperative patients recovering in general wards.“ Eur J Anaesthesiol 29(5): 251254.,15,第十五頁,共二十五頁。,Blaudszun, G., C. Lysakowski, et al. (2022). “Effect of perioperative systemic alpha2 agonists on postoperative morphine consumption and pain intensity: systematic review and metaanalysis of randomized controlled trials.“ Anesthesiology 116(6): 13121322.,納入30項(xiàng)研究,近1800例患者; CONCLUSIONS: Perioperative systemic alpha2 agonists decrease postoperative opioid consumption, pain intensity, and nausea. Recovery times are not prolonged. Common adverse effects are bradycardia and arterial hypotension. The impact of al