循環(huán)的microrna是早期診斷人類急性心肌梗死的潛在的新型生物標(biāo)志物(完整版)
【正文】 atients with AMI, with CHD, and nonCHD. Results Figure 4 Elevation of cardiacspeci?c microRNAs in plasma from acute myocardial infarction patients. (A) The plasma was collected from patients with acute myocardial infarction (n =33), patients with coronary heart disease but without acute myocardial infarction (coronary heart disease, n=16), patients with other cardiovascular disease (noncoronary heart disease, n= 17) and healthy volunteers (healt n =30). Total RNA was isolated, reversetranscribed and subjected to realtime polymerase chain reaction analysis. Dark lines represe mean or median values where appropriate (**P ). Results (B) The plasma was collected from ?ve patients with acute myocardial infarction after receiving 2 months of medical treatment. Results Figure 5 Evaluation of plasma microRNAs for the diagnosis of acute myocardial infarction. (A) Receiver operating characteristic curves were drawn with the data of plasma microRNAs from 66 patients with chest pain. AUC, the area under curve. (B) Sensitivity and speci?city of plasma microRNA levels in the diagnosis of acute myocardial infarction. The dashed line indicates a 100% speci?city thre
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