基于異腈的多組分反應(yīng)構(gòu)建功能化雜環(huán)化合物骨架(完整版)
【正文】 6(1methyl1Hindol3yl)4Hpyran3,4dicarboxylateMP 119121 oC1H NMR (DMSO, 400 MHz) δ (s, 1H), (s, 1H), (m, 2H), (t, 1H, J = 8 Hz), (t, 1H, J = 8 Hz), (s, 1H), (m, 4H), (s, 3H), (s, 9H), (t, 3H, J = 6 Hz), (t, 3H, J = 6 Hz).13C NMR (DMSO, 100 MHz) δ , , , , , , , , , , , , , , , , , , , , , , .IR(cm1) 3269,3118,2973,2209,1740,1674,1529,1434, 1380,1211,1041.HRMS (ESI) m/z Calc. Found .Diethyl5cyano2(cyclohexylamino)6(1methyl1Hindol3yl)4Hpyran3,4dicarboxylateMP 119123 oC1H NMR (DMSO, 400 MHz) δ (d, 1H, J = 8 Hz), (s, 1H), (d, 1H, J = 8 Hz), (d, 1H, J = 8 Hz), (t, 1H, J = 6 Hz), (t, 1H, J = 6 Hz), (m, 5H), (s, 3H), (m, 2H), (m, 2H), (m, 1H), (m, 12H).13C NMR (DMSO, 75 MHz) δ , , , , , , , , , , , , , , , , , , , , , , , , .IR( cm1) 3249,3162,2931,2860,2203,1750,1631,1527,1449, 1364,1171,1088.HRMS (ESI) m/z Calc. Found .Diethyl6(1benzyl1Hindol3yl)2(tertbutylamino)5cyano4Hpyran3,4dicarboxylateMP oC1H NMR (DMSO, 400 MHz) δ (s, 1H), (s, 1H), (d, 1H, J = 8 Hz), (m, 7H), (s, 2H), (s, 1H), (m, 4H), (s, 9H), (t, 3H, J = 6 Hz), (t, 3H, J = 6 Hz).13C NMR (DMSO, 75 MHz) δ , , , , , , , , , , , , , , , , , , , , , , , , , , .IR(cm1)3259,3163,2977,2207,1739,1667,1524,1447, 1377,1288,1186,1078.HRMS (ESI) m/z Calc. Found .Diethyl6(1benzyl1Hindol3yl)5cyano2(cyclohexylamino)4Hpyran3,4dicarboxylateMP oC1H NMR (DMSO, 400 MHz) δ (d, 1H, J = 8 Hz), (s, 1H), (d, 1H, J = 8 Hz), (d, 1H, J = 8 Hz), (m, 7H), (s, 2H), (s, 1H), (m, 4H), (m, 2H), (m, 2H), (m, 1H), (m, 12H).13C NMR (DMSO, 75 MHz) δ , , , , , , , , , , , , , , , , , , , , , , , , , , , .IR(cm1) 3283,3104,2931,2206,1744,1675,1529,1449, 1383,1283,1177,1078.HRMS (ESI) m/z Calc. Found .Diethyl2(tertbutylamino)5cyano6(1hexyl1Hindol3yl)4Hpyran3,4dicarboxylateMP oC1H NMR (DMSO, 300 MHz) δ (s, 1H), (s, 1H), (m, 2H), (m, 2H), (t, 2H, J = 6 Hz), (s, 1H), (m, 4H), (s, 9H), (m, 14H), (t, 3H, J = 6 Hz).13C NMR (DMSO, 100 MHz) δ , , , , , , , , , , , , , , , , , , , , , , , , , , .IR( cm1) 3262,3177,2956,2212,1740,1678,1531,1443,1381,1287,1197,1078. HRMS (ESI) m/z Calc. Diethyl5cyano2(cyclohexylamino)6(1hexyl1Hindol3yl)4Hpyran3,4dicarboxylateMP oC1H NMR (DMSO, 400 MHz) δ (d, 1H, J = 8 Hz), (s, 1H), (d, 1H, J = 8 Hz), (d, 1H, J = 8 Hz), (t, 1H, J = 8 Hz), (t, 1H, J = 8 Hz), (t, 2H, J = 6 Hz), (s, 1H), (m, 4H), (m, 2H), (m, 2H), (m, 2H), (m, 1H), (m, 18H), (t, 3H, J = 6 Hz).13C NMR (DMSO, 75 MHz) δ , , , , , , , , , , , , , , , , , , , , , , , , , , , , , .IR(cm1) 3247,3130,2933,2850,2200,1740,1675,1524,1452, 1373,1292,1163,1092.HRMS (ESI) m/z Calc. Found .Diethyl2(tertbutylamino)5cyano6(1(4methoxyphenyl)1Hindol3yl)4Hpyran3,4dicarboxylateMP 165167 oC1H NMR (DMSO, 300 MHz) δ (s, 1H), (s, 1H), (m, 1H), (m, 3H), (m, 2H), (d, 2H, J = 9 Hz), (s, 1H), (m, 4H), (s,3H), (s, 9H), (t, 3H, J = 6 Hz), (t, 3H, J = 6 Hz).13C NMR (DMSO, 100 MHz) δ , , , , , , , , , , , , , , , , , , , , , , , , , , .IR(cm1) 3248,3170,2975,2211,1730,1666,1518,1443,1360,1296,1199,1068.HRMS (ESI) m/z Calc. Found .Diethyl5cyano2(cyclohexylamino)6(1(4methoxyphenyl)1Hindol3yl)4Hpyran3,4dicarboxylateMP 131133 oC1H NMR (DMSO, 400 MHz) δ (d, 1H, J = 8 Hz), (s, 1H), (d, 1H
環(huán)評(píng)公示相關(guān)推薦
鄂ICP備17016276號(hào)-1