【正文】 .......................................................................164 能量衡算 ....................................................................................................16 反應(yīng)罐能量衡算 .............................................................................................................................16 比熱容的計(jì)算 .........................................................................................................................17 能量衡算 ...................................................................................................................................185 主要工藝設(shè)備計(jì)算 ......................................................................................19 工藝設(shè)備選型原則 ..........................................................................................................................19 工藝設(shè)備計(jì)算 ..................................................................................................................................19 醋化反應(yīng)釜 ...............................................................................................................................19 夾套的計(jì)算 .............................................................................................................................20 筒體的材料和壁厚 .................................................................................................................22 水壓試驗(yàn)及其強(qiáng)度校核 .........................................................................................................23 選擇釜體法蘭 .........................................................................................................................24 選用手孔、視鏡、溫度計(jì)、和工藝接管 .............................................................................25 攪拌器的設(shè)計(jì)計(jì)算 .................................................................................................................26 容器支座的選用計(jì)算 .............................................................................................................26 酸洗離心機(jī) ......................................................................................................................................26 水洗離心機(jī) ......................................................................................................................................26 振動(dòng)流化床干燥器 ..........................................................................................................................27 母液蒸餾罐 ......................................................................................................................................27 循環(huán)母液反應(yīng)罐 ..............................................................................................................................276 管道設(shè)計(jì) ....................................................................................................27 管道計(jì)算 ..........................................................................................................................................27 水楊酸的進(jìn)料管道的計(jì)算 .......................................................................................................28 酸酐的進(jìn)料管道的計(jì)算 ...........................................................................................................28 母液的管道進(jìn)料計(jì)算 ...............................................................................................................287 車間布置設(shè)計(jì) .............................................................................................29 概述 ..................................................................................................................................................29 車間布置設(shè)計(jì)的依據(jù) ......................................................................................................................29 車間布置設(shè)計(jì)應(yīng)考慮的因素 ..........................................................................................................30 車間布置設(shè)計(jì)的程序 ......................................................................................................................30 車間設(shè)計(jì)的成果 ..............................................................................................................................318 公用工程 ....................................................................................................31 排水系統(tǒng) ..........................................................................................................................................31 電氣和照明 .....................................................................................................................................33 電氣設(shè)計(jì)和安裝 .......................................................................................................................33 環(huán)境消毒 ..........................................................................................................................................33 滅菌與消毒 ...............................................................................................................................339 技術(shù)經(jīng)濟(jì) ....................................................................................................34 投資指標(biāo) ..........................................................................................................................................34設(shè)計(jì)體會(huì) ..........................................................................................................35參考文獻(xiàn) ..........................................................................................................361 概述阿司匹林是歷史悠久的解熱鎮(zhèn)痛藥，它誕生于 1899 年 3 月 6 日。工藝設(shè)計(jì)包括方案設(shè)計(jì)及物料恒算，熱量恒算，主要設(shè)備選型計(jì)算，車間布置設(shè)計(jì)，管路設(shè)計(jì)等。近年來(lái)，阿司匹林的適用范圍已從解熱鎮(zhèn)痛藥向心血管病預(yù)防用藥領(lǐng)域擴(kuò)展 ，在心血管病預(yù)防用藥量不斷增加的推動(dòng)下，其市場(chǎng)得到進(jìn)一步的上升空間。 二、重點(diǎn)設(shè)計(jì)問(wèn)題 ⑴文獻(xiàn)綜述及可行性報(bào)告； ⑵廠址選擇及車間總平面設(shè)計(jì)； ⑶車間工藝設(shè)計(jì)（內(nèi)容主要包括產(chǎn)品方案及生產(chǎn)方法的選擇、物料衡算、生產(chǎn)工藝流程設(shè)計(jì)、能量衡算、給水平衡、設(shè)備設(shè)計(jì)與選型、車間平面布置設(shè)計(jì)、管路設(shè)計(jì)等） ；