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【正文】 ise, end pregnancy – arterial, therefore more severe – mortality 3050% – higher rebleed mortality rate (13%) Hemorrhage ?AVM – rupture not a function of size – no marked increase with exercise, pregnancy, trauma – arteriovenous, therefore less severe – mortality 6 to % – lower rebleed mortality rate (1%) – vasospasm rare ?Aneurysm – rupture related to aneurysm size – increase with trauma exercise, end pregnancy – arterial, therefore more severe – mortality 3050% – higher rebleed mortality rate (13%) – vasospasm mon Hemorrhage AVM ?Noheless, risk of major, incapacitating, or fatal hemorrhage in untreated lesion is 40 to 50% Hemorrhage AVM ?Noheless, risk of major, incapacitating, or fatal hemorrhage in untreated lesion is 40 to 50% ?Yearly risk of initial hemorrhage ~3% ?Rebleed in first subsequent year 618%, reducing to ~3% again thereafter ?Pediatric prognosis worse than adult Spetzler amp。 Pathophysiology ?absence of normal capillary system ?usual function displaced ?asymptomatic at birth ?vessels change with time ?may develop aneurysms ?parenchymal changes within and around the lesion ?site frequency is proportional to brain volume Pathology amp。 Pathophysiology ?absence of normal capillary system Pathology amp。CEREBRAL ARTERIOVENOUS MALFORMATIONS AVM: a TLA for the CNS Incidence ?% at autopsy ?Slight male preponderance ( to ) ?Congenital lesions (although
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