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which analyses the fixture–work piece system subject to timevarying machining loads. The influence of clamping placement is also investigated. Li and Melkote[7]presented a fixture layout and clamping force optimal synthesis approach that accounts for work piece dynamics during machining. A bined fixture layout and clamping force optimization procedure presented. They used the contact elasticity modeling method that accounts for the influence of work piece rigid body dynamics during machining. Admiral et al. [8] used ANSYS to verify fixture design integrity. They employed 321 method. The optimization analysis is performed in ANSYS. Tan et al. [9] described the modeling, analysis and verification of optimal featuring configurations by the methods of force closure, optimization and finite element modeling. Most of the above studies use linear or nonlinear programming methods which often do not give global optimum solution. All of the fixture layout optimization procedures start with an initial feasible layout. Solutions from these methods are depending on the initial fixture layout. They do not consider the fixture layout optimization on overall work piece deformation. The GAs has been proven to be useful technique in solving optimization problems in engineering [10–12]. Fixture design has a large solution space and requires a search tool to find the best design. Few researchers have used the GAs for fixture design and fixture layout problems. Kumar et al. [13] have applied both GAs and neural networks for designing a fixture. Marcelin [14] has used GAs to the optimization of support positions. Vallapuzha et al. [15] presented GA based optimization method that uses spatial coordinates to represent the locations of fixture elements. Fixture layout optimization procedure was implemented using MATLAB and the genetic algorithm toolbox. HYPERMESH and MSC/NASTRAN were used for FE model. Vallapuzha et al. [16] presented results of an extensive investigation into the relative effectiveness of various optimization methods. They showed that continuous GA yielded the best quality solutions. Li and Shiu [17] determined the optimal fixture configuration design for sheet metal assembly using GA. MSC/NASTRAN has been used for fitness evaluation. Liao [18] presented a method to automatically select the optimal numbers of locators and clamps as well as their optimal positions in sheet metal assembly fixtures. Krishnakumar and Melkote [19] developed a fixture layout optimization technique that uses the GA to find the fixture layout that minimizes the deformation of the machined surface due to clamping and machining forces over the entire tool path. Locator and clamp positions are specified by node numbers. A builtin finite element solver was developed. Some of the studies do not consider the optimization of the layout for entire tool path and chip removal is not taken into account. Some of the studies used node numbers as design parameters. In this study, a GA tool has been developed to find the optimal locator and clamp positions in 2D work piece. Distances from the reference edges as design parameters are used rather than FEA node numbers. Fitness values of real encoded GA chromosomes are obtained from the results of FEA. ANSYS has been used for FEA calculations. A chromosome library approach is used in order to decrease the solution time. Developed GA tool is tested on two test problems. Two case studies are given to illustrate the developed approach. Main contributions of this paper can be summarized as follows:(1) developed a GA code integrated with a mercial finite element solver。 fitter individuals have better chances of transmitting their characteristics to later generations.In the algorithm, the selection of the natural environment is replaced by artificial selection based on a puted fitness for each design. The term fitness is used to designate the chromosome’s chances of survival and it is essentially the objective function of the optimization problem. The chromosomes that define characteristics of biological beings are replaced by strings of numerical values representing the design variables.GA is recognized to be different than traditional gradient based optimization techniques in the following four major ways [10]:1. GAs work with a coding of the design variables and parameters in the problem, rather than with the actual parameters themselves.2. GAs makes use of populationtype search. Many different design points are evaluated during each iteration instead of sequentially moving from one point to the next.3. GAs needs only a fitness or objective function value. No derivatives or gradients are necessary.4. GAs use probabilistic transition rules to find new design points for exploration rather than using deterministic rules based on gradient information to find these new points.4. Approach. Fixture positioning principlesIn machining process, fixtures are used to keep workpieces in a desirable position for operations. The most important criteria for featuring are work piece position accuracy and work piece deformation. A good fixture design minimizes work piece geometric and machining accuracy errors. Another featuring requirement is that the fixture must limit deformation of the work piece. It is important to consider the cutting forces as well as the clamping forces. Without adequate fixture support, machining operations do not conform to designed tolerances. Finite element analysis is a powerful tool in the resolution of some of these problems [22].Common locating method for prismatic parts is 321 method. This method provides the maximum rigidity with the minimum number of fixture elements. A work piece in 3D may be positively located by means of six points positioned so that they restrict nine degrees of freedom of the work piece. The other three degrees of freedom are removed by clamp elements. An example layout for 2D work piece ba