豬肺炎支原體的免疫時(shí)機(jī)及疫苗的選擇-wenkub
2023-01-21 06:11:10 本頁面
【正文】 干擾 ? Protection needs to last for entire finishing period ? 保護(hù)力需要持續(xù)整個(gè)育肥期 50 Lung Scores After Vaccination of Maternal Antibody Pigs At 4 And 6 Weeks of Age 0 0 5 10 15 20 % of lung lesions 4 weeks 6 weeks Nonvacc NonChall * Significantly lower than nonvaccinated, P * * 51 Efficacy of Vaccination of 1, 3, and 6 week old Pigs * 0 0 1 2 3 4 5 6 Mean pourcentage of Lung Consolidation 1 week 3 weeks 6 weeks Nonvacc Non Chall Age when vaccinated * Significantly lower than nonvaccinates , p = 52 Onedose vs.. Twodose 一針免疫還是二針免疫 ? Theoretical immunology tells us that with an inactivated vaccine, two doses are necessary to achieve peak immunity. This is very important with M. hyo since we want longlasting immunity. ? 根據(jù)免疫學(xué)理論，滅活苗二針免疫才能達(dá)到免疫力高峰。 31 Western Blot Analysis 免疫印記分析 ? M+Pac preserves 15 proteins ?安百克保留了 15種抗原蛋白 ? Product A preserves 11 proteins ? A產(chǎn)品保留了 11種抗原蛋白 ? Products B and C preserve 8 proteins ? B和 C產(chǎn)品保留了 8種抗原蛋白 32 M+PAC 安百克 擁 有全世界最多的 豬支原體 抗原 Pfizer Intervet Fort Dodge M+PAC 33 M. hyo Vaccines ? Also, because longlasting immunity is important, it is our belief that an effective M. hyo vaccine should have an improved oil adjuvant….. ? 此外，長久免疫力是重要的，良好的油佐劑是支原體疫苗必須的。 4 M. hyo Disease ? One of the primary pathogens causing Porcine Respiratory Disease Complex (PRDC) ?引起 PRDC 的原發(fā)病原之一 ? Affects as many as 99% of . herds ? 99％的美國豬群都有感染 ? Worldwide significance ?世界范圍內(nèi)養(yǎng)豬生產(chǎn)中流行 5 M. hyo disease ? Economic effects are extremely variable between herds. ?不同豬群的經(jīng)濟(jì)影響差異較大 ? Dependent on cost of inputs, price of pigs, other diseases, etc. ?取決于投入的成本、豬價(jià)、其它疾病的情況等。 ? A MOVING TARGET. 6 M. hyo Disease ? Reduced average daily gain (ADG) ? 降低日增重 ? Reduced feed efficiency (FE) ? 降低飼料報(bào)酬 ? Increased medication costs ? 增加藥物成本
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