egfr簡(jiǎn)介20xx年3月-wenkub
2023-05-21 13:07:08 本頁(yè)面
【正文】 ) 表皮素 (epiregulin， EPR) TK TK TK erbB1 HER1 EGFR erbB2 HER2 erbB3 HER3 erbB4 HER4 No specific ligands often acts as dimer partner Heregulins NRG2 NRG3 Heregulins βcellulin EGF, TGFa , b Cellulin Amphiregulin, HBEGF TK TK TK TK erbB1 HER1 EGFR erbB2 HER2 neu erbB3 HER3 erbB4 HER4 EGFR Homo Dimerisation TK TK TK erbB1 HER1 EGFR erbB2 HER2 neu erbB3 HER3 erbB4 HER4 Hetero Dimerisation 癌細(xì)胞 EGFR的作用機(jī)制 Gene Transcription G0 G1 Priming S G2 M Cell Cycle + 生長(zhǎng)因子在細(xì)胞周期中的作用 Receptors TK EGFR在正常細(xì)胞中 TK ATP ATP Cell Proliferation Antiapoptosis Angiogenesis Gene
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