急性犬瘟熱感染組織臟器的研究分析畢業(yè)論文(已修改)
2025-07-08 08:36 本頁面
【正文】 急性犬瘟熱感染組織臟器的研究摘 要臨床中的犬瘟熱病毒感染多為急性和亞急性型,犬年齡在6月齡左右,其癥狀和病毒復(fù)制的臟器都與慢性病例有很大區(qū)別。臨床上急性病例的主要病變集中在肺臟和淋巴組織,組織病理學(xué)觀察到犬淋巴結(jié)炎和多核巨細(xì)胞性肺炎。根據(jù)免疫組織化學(xué)染色結(jié)果發(fā)現(xiàn)在犬瘟熱急性病例的淋巴結(jié)皮質(zhì)犬瘟熱抗原呈強(qiáng)陽性,且密度很高。而在犬的肺臟雖然表現(xiàn)出嚴(yán)重的肺炎癥狀,但是犬瘟熱病毒抗原陽性反應(yīng)弱,僅在支氣管上皮和少量的巨噬細(xì)胞胞漿中觀察到。犬瘟熱病毒首先在犬的淋巴組織中進(jìn)行復(fù)制增殖, 破壞被膜下淋巴竇和淋巴小節(jié)中的T淋巴細(xì)胞和B淋巴細(xì)胞,影響淋巴組織輸出到外周血液循環(huán)中的淋巴細(xì)胞數(shù)量。結(jié)論:犬瘟熱病毒病雖然臨床上以肺臟病變最為嚴(yán)重,但是急性型和亞急性型的犬瘟熱病毒主要在淋巴組織的T淋巴細(xì)胞B淋巴細(xì)胞和巨噬細(xì)胞中增殖,所以應(yīng)該以淋巴組織作為犬瘟熱病毒的主要分離臟器。關(guān)鍵詞:犬瘟熱病毒,免疫組織化學(xué),淋巴結(jié)Infected tissue of acute organ of canine distemperAbstractThe canine distemper virus infection clinical for acute and subacutetype,dogs age 6 months or so, in its symptoms and the viscera iral replication with chronic cases have very big distinction. The main lesion clinical acute cases in the lungs and centralized lymphoid tissue, observed histopathologically to dog lymph node inflammation and multinucleated giant cells of pneumonia. According to immunohistochemical results found in your dog39。s distemper acute cases lymph nodes cortex your dog39。s distemper antigen is strong positive, and higher density. And in the lungs although dog show serious pneumonia symptoms, but canine distemper virus antigen positive reaction is weak, only in the bronchial epithelium and a small amount of macrophages observed in the cytoplasm. Canine distemper virus first in dogs in the lymphatic organization reproduced proliferation, damaging the
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