【正文】
169。2022 免疫學(xué)信息網(wǎng) 移 植 免 疫 學(xué) 169。2022 免疫學(xué)信息網(wǎng) History 169。2022 免疫學(xué)信息網(wǎng) EARLY EXPERIMENTS 1902 The first sucessful experimental kidney transplants were performed at the Vienna Medical School in Austria with animals. 169。2022 免疫學(xué)信息網(wǎng) 1909 The first kidney transplant experiments were performed in humans in France using animal kidneys. o A surgeon inserted slices of rabit kidney into a child suffering from kidney failure. Although “the immediate results were excellent” the child died about 2 weeks later. o While such transplants did sucessfully produce urine, they lasted only for about an hour before ceasing to function. o Scientists of the time believed kidney transplants were possible, but their success was limited by unknown “biochemical barriers,” which prevented longterm kidney survival 169。2022 免疫學(xué)信息網(wǎng) 1933 The first humantohuman kidney transplant was performed o Unknown to doctors at the time, there were mismatches in donor and recipient blood groups and the donor kidney never functioned 1940’s Sir Peter Medawar at the University of London experimented with the immunologic basis of an re