《measles麻疹》ppt課件-文庫吧
2025-01-04 19:28 本頁面
【正文】 ty or those havn’t used immune globulin 1. Incubation period (infection to symptoms) : 618days (average 10 days) 2. Prodromal period: ? 34 days ? Nonspecific symptoms: fever, malaise, anorexia, headache ? Classical triad: cough, coryza, conjunctivitis (with photophobia, lacrimation) CLINICAL MANIFESTATION Enanthem (Koplik spots): ? Pathognomonic for measles ? 2448 hr before rash appears ? 1mm, grayish white dots with slight, reddish areolae ? Buccal mucosa, opposite the lower 2nd molars ? fade soon after rash onset CLINICAL MANIFESTATION Koplik spots CLINICAL MANIFESTATION 3. Rash period 34days Exanthem: Erythematous, nonpruritic, maculopapular ? Upper lateral of the neck, behind ears, hairline, face ? trunk ? arms and legs ? The severity of the disease is directly related to the extent and confluence of the rash , CLINICAL MANIFESTATION CLINICAL MANIFESTATION CLINICAL MANIFESTATION CLINICAL MANIFESTATION Temperature: ? Rises abruptly as the rash appears ? Reaches 40℃ or higher ? Settles after 45 days – if persists, suspect secondary infection Coryza, fever, and cough: ? Increasingly severe up to the time the rash has covered the body Lymphadenopathy (posterior cervical region, mesenteric) splenomegaly, diarrhoea, vomiting Chest X ray: ? May be abnormal, even in unplicated cases CLINICAL MANIFESTATION 4. Recovery period 34days Exanthem: ? Fades in order of appearance ? Branny desquamation and brownish discoloration Entire illness – 10 days CLINICAL MANIFESTATION CLINICAL MANIFESTATION Atypical Manifestation: 1. Mild measles ? In patients: administered immune globulin products during the incubation period and immunized against measles。 in infants 8mo ? Long incubation period and short prodromal phase ? Mild symptom ? No Koplik spot ? The rash tends to be faint ? No branny desquamation and brownish discoloration occur as the rash fades ? No plications and short course CLINICAL MANIFESTATION 2. Severe measles: ? In cases with malnutrition, hypoimmunity and
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