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ve effect on mortality but no significant effect after adjustment for postAKI fluid balance. ? There was no threshold dose of furosemide above which mortality increased Conclusions ? A positive fluid balance after AKI was strongly associated with mortality. ? PostAKI diuretic therapy was associated with 60day patient survival in FACTT patients with ALI。 Fluid Balance, Diuretic Use, and Mortality in Acute Kidney Injury Man E. Grams,*? Michelle M. Estrella,* Josef Coresh,*??, Roy G. Brower,* and Kathleen D. Liu167。 for the National Heart, Lung, and Blood Institute Acute Respirator