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? 因應(yīng) BZD receptor agonists(特別是 ZOLPIDEM)近年大量使用之趨勢,宜有全面性、系統(tǒng)性的評估,以證實其療效並瞭解可能的不良反應(yīng),必要時制定相關(guān)使用準則,以確保治療效果及用藥安全。 ? BZD receptor agonists是否依賴性與成癮性均優(yōu)於傳統(tǒng)的 BZD,雖有報告 *,仍有待更多資料檢驗。 ? 預(yù)定連續(xù)分析數(shù)年 (2023~2023)健保資料,探討變化趨勢。3:7386. 臺灣鎮(zhèn)靜安眠類藥品使用盛行率 以及相關(guān)後遺癥之研究 ? 行政院衛(wèi)生署管制藥品管理局九十六年度委託科技研究計畫報告 ,民國 97年 ,吳佳璇、張家銘、張憶壽、林克明、賴虹均、王金龍、蔡芳榆。ger D, Poursain B. Curr Med Res Opin. 2023。65(suppl 16):2326. Insomnia: Challenges for Physicians ? In an international study of consequences of insomnia over a 12month period – Many respondents took no action to alleviate their insomnia symptoms, and this may be due to fear of the implications of treatment, including the possible risks of dependence on medications – Focus groups of patients describing their insomnia experience reported that they felt that the impact of insomnia on their lives was pervasive and misunderstood by others who were significant to them or treating their sleep plaints ? More research is necessary to determine the longterm effects of insomnia treatments ? Current treatment options do not address the needs of difficulttotreat patients with chronic insomnia, such as the elderly, and those with orbid medical and psychiatric conditions. Benca RM. Psychiatr Serv. 2023。56:332–343. AncoliIsrael S, Roth T. Sleep. 1999。 nonBDZ RD: 。 ADP: minutes。 nonBDZ: minutes。 95% CI: , ). Sleep onset latency assessed by sleep diaries was also improved (BDZ: minutes。 95% CI: , ), nonbenzodiazepines (nonBDZ) ( minutes。22(9):133550. Epub 2023 Jul 10 ? BACKGROUND: Hypnotics have a role in the management of acute insomnia。43:11–19. Therapeutic Goals in Treating Insomnia Sleep Onset Sleep Maintenance ? Number of awakenings ? Duration of awakenings ? Time to fall asleep Sleep Duration ? Total sleep time ? Alertness ? Functioning ? Vitality NextDay Functioning Initial Screening ? Nature of plaint ? Daytime consequences ? Frequency ? Duration ? Precipitating events ? Exacerbating factors ? Sleepwake schedule ? Other nocturnal symptoms ? Associated behaviors ? Cognitions ? Previous treatments ? Psychiatric disorders ? Substance abuse ? Conitant medications ? Medical/neurological illness ? Other sleep disorders Assessment of Insomnia Additional History for Persistent Insomnia Chronic Insomnia: Treatment Considerations TREATMENT Cognitive Behavioral Therapy (CBT) Benzodiazepine Receptor Agonist ? Benzodiazepines ?NonBenzodiazepines Antidepressants* Atypical Antipsychotics* OTC Alternative Meds: Melatonin and Herbal Remedies *Not FDA approved for treatment of insomnia NIH Statement. Sleep. 2023。62(suppl 10):1826. Greater Impaired Function Impact of Insomnia on Physical and Emotional Health and Social Functioning 35557595C on t rol I n s om n i aB o d y Pa i nG en er al H eal t hM en t al H eal t hR o l e E m o t i o n alR o l e Ph y s i c alS o c i al F u n c t i o n i n gV i t al i t yPh y s i c al F u n c t i o n i