郭yl范可尼綜合征韋尼克綜合征(參考版)
2024-08-26 14:31本頁面
【正文】 ?WE三聯(lián)征（ 17%）：意識(shí)狀態(tài)改變（ 82%）、眼肌麻痹、共濟(jì)失調(diào)（ 23%） ?KS特點(diǎn)：即刻記憶存在，但近事和長(zhǎng)期記憶能力喪失，有時(shí)對(duì) 遠(yuǎn)期事件的記憶力仍存在 ?病因：酗酒（ 90%）、厭食、劇吐、全腸外營(yíng)養(yǎng)、惡液質(zhì) ?影像學(xué)特征： 乳頭體萎縮 （ 80%）；室周、第三腦室、內(nèi)側(cè)丘腦、 乳頭體 T1增加， T2減少 韋尼克 科薩科夫綜合征 ?原則：立即進(jìn)行，不必等待確診結(jié)果 ?戒酒、去除誘因、補(bǔ)充 VB1 ?推薦方案： VB1 100200mg Qd im/iv 5d 聯(lián)合或序貫 VB1 100mg Qd po ?大劑量方案： VB1 500mg tid im/iv 阿德福韋不良反應(yīng) ?In patients with pensated liver disease, the most monly reported side effects were asthenia, headache, abdominal pain, and nausea during 48 weeks of therapy. In patients with depensated liver disease, the most monly reported side effects were increased creatinine and asthenia during up to 203 weeks of therapy. ?Renal： Very mon (10% or more): Increased serum creatinine； Common (1% to 10%): Renal failure, abnormal renal function； Frequency not reported: Renal toxicity, changes in renal function, renal events, renal insufficiency, renal calculus, renal pain,
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