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注:與正常對照組比較, * p ; ** p Probiotics Many Potential Uses ? Infectious diarrhea and day care related illness ? Antibiotic Associated Diarrhea – Clostridium difficile ? Inflammatory bowel disease ? Traveler’s diarrhea ? Prevention of NEC ? Allergy ? Irritable Bowel Syndrome Yogurt (364) Yogurt+ L. casei (360) Pvalue Children with diarrhea 87 (22%) 61 (16%) Duration of diarrhea (days) Rotavirus positive stool % % Prevention of Diarrheal Illness 18 Week Therapy in French Children (624 months) in Day Care CA Pedone, et al. Int J Clin Pract 54(9):56871, 2022 Controls (60) B. lactis (73) L. reuteri (68) Pvalue Days with diarrhea Episodes of diarrhea Clinic visits Absences Prevention of Diarrheal Illness 12 Week Therapy in Israeli Infants in Day Care Z Weizman, et al. Pediatrics 115:59, 2022 Controls (58) Lactobacillus GG (61) Pvalue Children with diarrhea 9 (16%) 3 (5%) Duration of diarrhea (days) 4 4 NS Stool frequency (per day) 5 5 NS Prevention of Diarrheal Illness (After Antibiotics for Respiratory Illness) 2 Week Therapy in Finnish Children (2 weeks to 12 years) T Arvola, et al. Pediatrics 104(5), 1999 Probiotics Antibiotic Associated Diarrhea ? S. boulardii – Reduced rate of diarrhea in 116 patients ve