氨基葡萄糖word版-資料下載頁(yè)
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【正文】 03)000529. PMID12801482.）（Chan PS, Caron JP, Orth MW (November 2005). Effect of glucosamine and chondroitin sulfate on regulation of gene expression of proteolytic enzymes and their inhibitors in interleukin1challenged bovine articular cartilage explants. American Journal of Veterinary Research 66 (11): 1870–6. doi:16334942）（Uitterlinden EJ, Jahr H, Koevoet JL et al. (March 2006). Glucosamine decreases expression of anabolic and catabolic genes in human osteoarthritic cartilage explants. Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society 14 (3): 250–7. doi:16300972.）（Chu SC, Yang SF, Lue KH et al. (October 2006). Glucosamine sulfate suppresses the expressions of urokinase plasminogen activator and inhibitor and gelatinases during the early stage of osteoarthritis. Clinica Chimica Acta。 International Journal of Clinical Chemistry 372 (1–2): 167–72. doi:16756968.）（擴(kuò)充：GS可以刺激蛋白聚糖核心蛋白mRNA和蛋白質(zhì)水平，并在同一時(shí)間從OA的關(guān)節(jié)軟骨的軟骨細(xì)胞，抑制基質(zhì)降解的MMP 3的生產(chǎn)和酶的活動(dòng)。這些結(jié)果提供了令人信服的分子機(jī)制，以支持臨床觀(guān)察表明GS可能有一個(gè)有利的影響的一些骨關(guān)節(jié)炎患者的關(guān)節(jié)軟骨損失的預(yù)防。
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