【正文】
, Seiki M, et al. Heat shockmediated transient increase in intracellular3’,5’cyclic ampresults in tumor specofic suppression of membrane type 1martix metalloproteinase production and progelatinase a activation. Clin Exp Metastasis, 2000, 18: 131138. 6 Evans SS, Wang WC, Bain MD, et al. Feverrange hyperthermia dynamically regulates lymphocyte delivery to high endothelial venules. Blood, 2001, 97:27272733. 7 Burd R, Dziedzic TS, Xu Y, et al. Tumor cellapoptosis lymphocyte recruitment and tumor vascular change are induced by low temperation, long due/ration (feverlike) while body hyperthermia. J Cell Physiol, 1998, 177:137147. 8 Huang GW, Masanori S, Li JE, et al. The relationship between microvessel density the expression of vascular endothelial growth factor(VEGF), and the extension of nasopharyngeal carcinoma. Laryngoscope, 2000,110:20662069. 9 Sawaji Y, Sato T, Takeuchi A, et al. Antiangiogenic action of hyperthermia by suppressing geneexpression and production of tumourderived vascular endothelial growth factor in vivo and invitro. Br J Cancer, 2002, 86:15971603. 10 Wiedemann GJ, Robins HI, Katschinski DM, et al. Systemic hyperthermia and ICE chemotherapy for sara patients: rationale and clinical status. Anticancer Res, 1997,17:28892902. 11 Hildebrandt B, Wust P, Ahlers O, et al. The cellular and molecular basis of hyperthermia. Crit Rev Oncol Hematol, 2002,43:3356. 12 Katschinski DM, Wiedemann GJ, Mlongo W, et al. Whole body hyperthermia cytokine induction: a review, and unifying hypothesis for myeloprotection in the setting of cytotoxic therapy. Cytokine Growth Factor Rev,1999,10:9397. 13 Sminia P, Zee J, Wondergem J, et al. Effect of hyperthermia on the central nervous system: a review. Int J Hyperthermia, 1994, 10: 130.15 /