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城市>農(nóng)村 ③ Rural, not very high, but the increasing rate is rapid ④ No gender difference in preschool. Higher in boys than girls in schoolage ⑤ Agespecial: 1yr have light peak, after that reduce with age increase, 5yr rebound, 1013yrs reach the peak ?Many adulthood obesity develop from from childhood obesity. ?Risk : Obesity children develop into adulthood obesity ? Infant 14 % ? 7 yrs child 41 % ? 10~ 13 80 % China ? Higher stunt prevalence ? With the improvement of nutrition, the stunting tend to catchup growth, and tend to obese late pregnancy, fetus absorb much energy — high BMI obesity ? Excess feeding to infants — weight increase fast — adipose early rebound 脂肪早期重聚 — early maturation pattern puberty — central and high BMI obesity developing country and shift society Trend in underweight prevalence from 1990 to 2022, by region The trend analysis is based on a subset of 76 countries with trend data, covering 83 per cent of the underfive population in the developing world. For CEE/CIS, the baseline year is 1996。 data availability was limited for the period around 1990. Prevalence was estimated using NCHS/WHO/CDC reference population V. Factors ( Etiology) Obesity: A Complex Disease Causes of childhood obesity ?GeneGene: linkage and interaction ?Gene—Environment: cooperation and interaction ?Environment Diet: energy, diet structure, soft drink Socioeconomic status Physical exercise Lifestyle (sedentary) Commercial inducement 1. Geic determinants 遺傳因素 ? In the twins studies, the heritability of the BMI was estimated to be very high, about 80%. ? The results of adoption and family studies, however, agree on a heritability of about 33%. Geic predisposition ? ob gene ? leptin 2. Environmental determinants 環(huán)境因素 ① Food intake ② Socioeconomic status ③ Family factors ④ Physical activity ⑤ Brain damage ⑥ Drugs ⑦ Endocrine factors ⑧ Psychologic factors (1) Newborn and infancy