【醫(yī)學課件】allhat研究ppt課件(留存版)
【正文】 Secondary Endpoints Chlorthalidone JAMA 2021。288:29812997 ALLHAT ： ； :； ： . Clinical trial 42,418 patients with hypertension ? SBP 140mmHg and/or DBP 90 mmHg OR ? Took medication for hypertension and had at least one additional risk factor for CHD ? Age 55 years ? NHLBI funded trial Diuretic Chlorthalidone 1225 mg/day (n=15,255) Endpoints: ? Primary – Fatal coronary heart disease and nonfatal MI ? Secondary – Allcause mortality, stroke, and major cardiovascular disease events (CHF, coronary revascularization, angina, and peripheral artery disease) ? Mean followup years ALLHAT JAMA 2021。288:29812997 Amlodipine 7 . 7 %1 0 . 2 %0%5%10%15%Heart Failure
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